Aktuelle Publikationen

2024

Drexler R, Ricklefs FL, Ben-Haim S, Rada A, Wörmann F, Cloppenborg T, et al. Defining benchmark outcomes for mesial temporal lobe epilepsy surgery: A global multicenter analysis of 1119 cases. Epilepsia 2024.

Kerestes R, Perry A, Vivash L, O'Brien TJ, Alvim MKM, Arienzo D, et al. Patterns of subregional cerebellar atrophy across epilepsy syndromes: An ENIGMA-Epilepsy study. Epilepsia 2024.

Pukropski J, Baumann J, Jordan A, Bausch M, Wrede R von, Surges R. Short-term effects of transcutaneous auricular vagus nerve stimulation on T-wave alternans in people with focal epilepsy - An exploratory pilot study. Epilepsy & behavior reports 2024; 26: 100657.

Reiter JT, Schulte F, Bauer T, David B, Endler C, Isaak A, et al. Evidence for interictal blood-brain barrier dysfunction in people with epilepsy. Epilepsia 2024.

Roll W, Bauer J, Dik A, Mueller C, Backhaus P, Räuber S, et al. 18FDPA-714-PET-MRI reveals pronounced innate immunity in human anti-LGI1 and anti-CASPR2 limbic encephalitis. J Neurol 2024.

Ryvlin P, Barba C, Bartolomei F, Baumgartner C, Brazdil M, Fabo D, et al. Grading system for assessing the confidence in the epileptogenic zone reported in published studies: A Delphi consensus study. Epilepsia 2024.

Sanders MW, van der Wolf I, Jansen FE, Aronica E, Helmstaedter C, Racz A, et al. Outcome of Epilepsy Surgery in MRI-Negative Patients Without Histopathologic Abnormalities in the Resected Tissue. Neurology 2024; 102: e208007.

Wartmann H, Effenberger T, Klähn H, Volmer T, Surges R. Inzidenz des plötzlichen Epilepsietodes (SUDEP): Update und Limitationen. Der Nervenarzt 2024.

2023

Ahmad N et al. (2023) De Novo Variants in RAB11B Cause Various Degrees of Global Developmental Delay and Intellectual Disability in Children. Pediatr Neurol 148:164–171.

Anders S, Breithausen B, Unichenko P, Herde MK, Minge D, Abramian A, Behringer C, Deshpande T, Boehlen A, Domingos C, Henning L, Pitsch J, Kim Y-B, Bedner P, Steinhäuser C, Henneberger C (2023) Epileptic activity triggers rapid ROCK1-dependent astrocyte morphology changes. Glia. doi:10.1002/glia.24495.

Andrzejak RG, Zaveri H, Schulze-Bonhage A, Leguia MG, Stacey WC, Richardson MP, Kuhlmann L, Lehnertz K (2023) Seizure forecasting: Where do we stand? Epilepsia. doi:10.1111/epi.17546.

Bauer T, Reiter JT, Enders S, Keil VCW, Radbruch A, Helmstaedter C, Surges R, Rüber T (2023) Subcortical grey matter volume and asymmetry in the long-term course of Rasmussen's encephalitis. Brain Commun 5:fcad324.

Baumgartner TR, Surges R (2023) Synkope, epileptischer oder psychogener Anfall? Der Weg zur richtigen Diagnose. Allgemeinmedizin up2date 04:106–112.

Baumgartner TR, Surges R (2023) Synkope, epileptischer oder psychogener Anfall? Der Weg zur richtigen Diagnose. Neurologie up2date 06:215–221.

Birtel J, Bauer T, Pauleikhoff L, Rüber T, Gliem M, Charbel Issa P (2023) Fundus autofluorescence imaging using red excitation light. Sci Rep 13:9916.

Blanco Portillo A, García-Caballero R, Real de Asúa D, Olaciregui Dague K, Herreros B (2023) What Ethics Support for Resolving Ethical Conflicts Do Internists Use in Spanish Hospitals? J Bioeth Inq. doi:10.1007/s11673-023-10276-1.

Bröhl T, Rings T, Pukropski J, Wrede R von, Lehnertz K (2023) The time-evolving epileptic brain network: concepts, definitions, accomplishments, perspectives. Front Netw Physiol 3:1338864.

Bröhl T, Wrede R von, Lehnertz K (2023) Impact of biological rhythms on the importance hierarchy of constituents in time-dependent functional brain networks. Front Netw Physiol 3:1237004.

Chang AJ, Roth R, Bougioukli E, Rüber T, Keller SS, Drane DL, Gross RE, Welsh J, Abrol A, Calhoun V, Karakis I, Kaestner E, Weber B, McDonald C, Gleichgerrcht E, Bonilha L (2023) MRI-based deep learning can discriminate between temporal lobe epilepsy, Alzheimer's disease, and healthy controls. Commun Med (Lond) 3:33.

Cucchi D, Walter SG, Baumgartner T, Menon A, Egger L, Randelli PS, Surges R, Wirtz DC, Friedrich MJ (2023) Poor mid-term clinical outcomes and a high percentage of unsatisfying results are reported after seizure-related shoulder injuries, especially after posterior proximal humerus fracture-dislocations. J Shoulder Elbow Surg. doi:10.1016/j.jse.2023.09.023.

Derner M, Reber TP, Faber J, Surges R, Mormann F, Fell J (2023) A key role of the hippocampal P3 in the attentional blink. Neuroimage:120028.

Fell J, Chaieb L, Hoppe C (2023) Mind wandering in anxiety disorders: A status report. Neurosci Biobehav Rev 155:105432.

Fischbach L, Bauer T, Diers K, Witt J-A, Brugues M, Borger V, Schidlowski M, Rácz A, Baumgartner T, Wrede R von, Paech D, Weber B, Radbruch A, Vatter H, Becker AJ, Huppertz H-J, Helmstaedter C, Surges R, Reuter M, Rüber T (2023) A novel geometry‐based analysis of hippocampal morphometry in mesial temporal lobe epilepsy. Human Brain Mapping hbm.26392. doi:10.1002/hbm.26392.

Frauscher B, Mansilla D, Abdallah C, Astner-Rohracher A, Beniczky S, Brazdil M, Gnatkovsky V, Jacobs J, Kalamangalam G, Perucca P, Ryvlin P, Schuele S, Tao J, Wang Y, Zijlmans GJM, McGonigal A (2023) Learn how to interpret and use intracranial EEG findings. Epileptic Disord:Online ahead of print.

Gallus M et al. (2023) Translational imaging of TSPO reveals pronounced innate inflammation in human and murine CD8 T cell-mediated limbic encephalitis. Sci Adv 9:eabq7595.

Galvis-Montes DS, van Loo KMJ, van Waardenberg AJ, Surges R, Schoch S, Becker AJ, Pitsch J (2023) Highly dynamic inflammatory and excitability transcriptional profiles in hippocampal CA1 following status epilepticus. Sci Rep 13:22187.

Han CZ, Donoghue T, Cao R, Kunz L, Wang S, Jacobs J (2023) Using multi-task experiments to test principles of hippocampal function. Hippocampus 33:646–657.

Hanafy AS, Steinlein P, Pitsch J, Silva MH, Vana N, Becker AJ, Graham ME, Schoch S, Lamprecht A, Dietrich D (2023) Subcellular analysis of blood-brain barrier function by micro-impalement of vessels in acute brain slices. Nat Commun 14:481.

Harms A, Bauer T, Witt J-A, Baumgartner T, Wrede R von, Rácz A, Ernst L, Becker AJ, Helmstaedter C, Surges R, Rüber T (2023) Mesiotemporal Volumetry, Cortical Thickness, and Neuropsychological Deficits in the Long-term Course of Limbic Encephalitis. Neurol Neuroimmunol Neuroinflamm 10.

Held NR, Bauer T, Reiter JT, Hoppe C, Keil VCW, Radbruch A, Helmstaedter C, Surges R, Rüber T (2023) Globally altered microstructural properties and network topology in Rasmussen's encephalitis. Brain Commun 5:fcad290.

Helmstaedter C, Meschede C, Mastani S, Moskau-Hartmann S, Rademacher M, Wrede R von, Witt J-A (2023) Normalization and cross-sectional validation of an extended Adverse Event Profile (E AEP) in a large cohort of patients with epilepsy. Seizure 114:9–17.

Hentschel M, Stoffel-Wagner B, Surges R, Wrede R von, Dolscheid-Pommerich RC (2023) The value of drug level concentrations of brivaracetam, lacosamide and perampanel in the care of people with epilepsy. Epilepsia. doi:10.1111/epi.17873.

Hoppe C, Beeres K, Witt J-A, Sassen R, Helmstaedter C (2023) How are they doing as adults? Psychosocial and socioeconomic outcomes 11-30 years after pediatric epilepsy surgery. Epilepsia Open. doi:10.1002/epi4.12736.

Houta S, Bader A, Effert J-S, Esser B, Henze J, Spaic A, Zocher F, Lauerer M, Surges R (2023) Digital health applications in the self‐management of epilepsy – a survey on patients’ perspective. Epilepsia Open epi4.12788. doi:10.1002/epi4.12788.

Jiruska P, Freestone D, Gnatkovsky V, Wang Y (2023) An update on the seizures beget seizures theory. Epilepsia. doi:10.1111/epi.17721.

Kar S, Perrelli A, Bali KK, Mastrocola R, Kar A, Khan B, Gand L, Nayak A, Hartmann C, Kunz WS, Samii A, Bertalanffy H, Retta SF (2023) Identification of galectin-3 as a novel potential prognostic/predictive biomarker and therapeutic target for cerebral cavernous malformation disease. Genes Dis 11:67–71.

Kutter EF, Dehnen G, Borger V, Surges R, Mormann F, Nieder A (2023) Distinct neuronal representation of small and large numbers in the human medial temporal lobe. Nat Hum Behav. doi:10.1038/s41562-023-01709-3.

Lehnertz H, Broehl T, Rings T, Wrede R von, Lehnertz K (2023) Modifying functional brain networks in focal epilepsy by manual visceral-osteopathic stimulation of the vagus nerve at the abdomen. Front Netw Physiol 3:1205476.

Lehnertz K (2023) Ordinal methods for a characterization of evolving functional brain networks. Chaos 33:22101.

Lehnertz K, Bröhl T, Wrede R von (2023) Epileptic-network-based prediction and control of seizures in humans. Neurobiol Dis 181:106098.

Müller P, Dietrich D, Schoch S, Pitsch J, Becker AJ, Cases-Cunillera S (2023) Ganglioglioma cells potentiate neuronal network synchronicity and elicit burst discharges via released factors. Neurobiol Dis 190:106364.

Neuhaus E, Bitzer F, Held NR, Bauer T, Gaubatz J, Wrede R von, Baumgartner T, Rácz A, Becker V, Surges R, Rüber T (2023) Volumetric gray matter findings in autonomic network regions of people with focal epilepsy. J Neuroimaging. doi:10.1111/jon.13164.

Olaciregui Dague KR, Witt J-A, Wrede R von, Helmstaedter C, Surges R (2023) DBS of the ANT for refractory epilepsy: A single center experience of seizure reduction, side effects and neuropsychological outcomes. Front Neurol 14:1106511.

Peltola J et al. (2023) Deep Brain Stimulation of the Anterior Nucleus of the Thalamus in Drug Resistant Epilepsy in the MORE Multicenter Patient Registry. Neurology. doi:10.1212/WNL.0000000000206887.

Peltola J, Surges R, Voges B, Oertzen TJ von (2023) Expert opinion on diagnosis and management of epilepsy-associated comorbidities. Epilepsia Open. doi:10.1002/epi4.12851.

Pertz M et al. (2023) Long-term neurocognitive function and quality of life after multimodal therapy in adult glioma patients: a prospective long-term follow-up. J Neurooncol. doi:10.1007/s11060-023-04419-y.

Pesämaa I, Müller SA, Robinson S, Darcher A, Paquet D, Zetterberg H, Lichtenthaler SF, Haass C (2023) A microglial activity state biomarker panel differentiates FTD-granulin and Alzheimer's disease patients from controls. Mol Neurodegener 18:70.

Reber TP, Mackay S, Bausch M, Kehl MS, Borger V, Surges R, Mormann F (2023) Single-neuron mechanisms of neural adaptation in the human temporal lobe. Nat Commun 14:2496.

Reiss Y, Bauer S, David B, Devraj K, Fidan E, Hattingen E, Liebner S, Melzer N, Meuth SG, Rosenow F, Rüber T, Willems LM, Plate KH (2023) The neurovasculature as a target in temporal lobe epilepsy. Brain Pathol:e13147.

Schuch F et al. (2023) An open presurgery MRI dataset of people with epilepsy and focal cortical dysplasia type II. Sci Data 10:475.

Schulte F, Bitzer F, Gärtner FC, Bauer T, Wrede R von, Baumgartner T, Rácz A, Borger V, Oertzen TJ von, Vatter H, Essler M, Surges R, Rüber T (2023) The diagnostic value of ictal SPECT - a retrospective, semiquantitative monocenter study. Epilepsia Open. doi:10.1002/epi4.12694.

Shamanskiy V et al. (2023) Secondary structure of the human mitochondrial genome affects formation of deletions. BMC Biol 21:103.

Staresina BP, Niediek J, Borger V, Surges R, Mormann F (2023) How coupled slow oscillations, spindles and ripples coordinate neuronal processing and communication during human sleep. Nat Neurosci. doi:10.1038/s41593-023-01381-w.

Trombly G, Said AM, Kudin AP, Peeva V, Altmüller J, Becker K, Köhrer K, Zsurka G, Kunz WS (2023) The Fate of Oxidative Strand Breaks in Mitochondrial DNA. Antioxidants (Basel) 12.

Walger L, Adler S, Wagstyl K, Henschel L, David B, Borger V, Hattingen E, Vatter H, Elger CE, Baldeweg T, Rosenow F, Urbach H, Becker AJ, Radbruch A, Surges R, Reuter M, Cendes F, Wang ZI, Huppertz H-J, Rüber T (2023) Artificial Intelligence for the Detection of Focal Cortical Dysplasia: Challenges in Translating Algorithms into Clinical Practice. Epilepsia. doi:10.1111/epi.17522.

Wenzel M, Huberfeld G, Grayden DB, Curtis M de, Trevelyan AJ (2023) A debate on the neuronal origin of focal seizures. Epilepsia. doi:10.1111/epi.17650.

Witt J-A, Becker AJ, Helmstaedter C (2023) The multifactorial etiology of cognitive deficits in epilepsy and the neuropathology of mesial temporal lobe epilepsy beyond hyperphosphorylated tau. Alzheimers Dement. doi:10.1002/alz.13085.

Wrede R von, Witt J-A, Auvin S, Devlin A, Lagae L, Marson A, Meador KJ, O Brien TJ, Park J, Surges R, Trinka E, Wiebe S, Helmstaedter C (2023) Unjustified allegation on cancer risks in children of mothers with epilepsy taking high-dose folic acid during pregnancy - No proof of a causal relationship. Epilepsia. doi:10.1111/epi.17680.

Wrede R von, Witt J-A, Helmstaedter C (2023) Big Data - Big Trouble: The two faces of publishing results from big data studies based on cohorts with poor clinical definition. Seizure 111:21–22.

Zatcepin A, Kopczak A, Holzgreve A, Hein S, Schindler A, Duering M, Kaiser L, Lindner S, Schidlowski M, Bartenstein P, Albert N, Brendel M, Ziegler SI (2023) Machine learning-based approach reveals essential features for simplified TSPO PET quantification in ischemic stroke patients. Z Med Phys. doi:10.1016/j.zemedi.2022.11.008.

Zsurka G, Appel MLT, Nastaly M, Hallmann K, Hansen N, Nass D, Baumgartner T, Surges R, Hartmann G, Bartok E, Kunz WS (2023) Loss of the Immunomodulatory Transcription Factor BATF2 in Humans Is Associated with a Neurological Phenotype. Cells 12.

Zsurka G, Trombly G, Schöler S, Blei D, Kunz WS (2023) Functional Assessment of Mitochondrial DNA Maintenance by Depletion and Repopulation Using 2',3'-Dideoxycytidine in Cultured Cells. Methods Mol Biol 2615:229–240.

2022

Adams T, Wagner S, Baldinger M, Zellhuber I, Weber M, Nass D, Surges R (2022) Accurate detection of heart rate using in-ear photoplethysmography in a clinical setting. Front Digit Health 4:909519.

Asadi-Pooya AA et al. (2022) Counseling about sudden unexpected death in epilepsy (SUDEP): A global survey of neurologists' opinions. Epilepsy Behav 128:108570.

Asúa DR de, Olaciregui Dague K, Arriaga A, Herreros B (2022) Animating Clinical Ethics: A Structured Method to Teach Ethical Analysis Through Movies. HEC Forum. doi:10.1007/s10730-022-09470-2.

Bahna M, Hamed M, Ilic I, Salemdawod A, Schneider M, Rácz A, Baumgartner T, Güresir E, Eichhorn L, Lehmann F, Schuss P, Surges R, Vatter H, Borger V (2022) The necessity for routine intensive care unit admission following elective craniotomy for epilepsy surgery: a retrospective single-center observational study. J Neurosurg:1–7.

Barker-Haliski M, Pitsch J, Galanopoulou AS, Köhling R (2022) A companion to the preclinical common data elements for phenotyping seizures and epilepsy in rodent models. A Report of the TASK3-WG1C: Phenotyping Working Group of the ILAE/AES Joint Translational Task Force. Epilepsia Open. doi:10.1002/epi4.12676.

Baumgartner T, Pitsch J, Olaciregui-Dague K, Hoppe C, Racz A, Rüber T, Becker A, Wrede R von, Surges R (2022) Seizure underreporting in LGI1 and CASPR2 antibody encephalitis. Epilepsia. doi:10.1111/epi.17338.

Belardi A, Chaieb L, Rey-Mermet A, Mormann F, Rothen N, Fell J, Reber TP (2022) On the relationship between mind wandering and mindfulness. Sci Rep 12:7755.

Borger V, Hamed M, Bahna M, Rácz Á, Ilic I, Potthoff A-L, Baumgartner T, Rüber T, Becker A, Radbruch A, Mormann F, Surges R, Vatter H, Schneider M (2022) Temporal lobe epilepsy surgery: Piriform cortex resection impacts seizure control in the long-term. Ann Clin Transl Neurol. doi:10.1002/acn3.51620.

Bröhl T, Lehnertz K (2022) A straightforward edge centrality concept derived from generalizing degree and strength. Sci Rep 12:4407.

Campbell C et al. (2022) A pharmacogenomic assessment of psychiatric adverse drug reactions to levetiracetam. Epilepsia 63:1563–1570.

Cases-Cunillera S, van Loo KMJ, Pitsch J, Quatraccioni A, Sivalingam S, Salomoni P, Borger V, Dietrich D, Schoch S, Becker AJ (2022) Heterogeneity and excitability of BRAFV600E-induced tumors is determined by Akt/mTOR-signaling state and Trp53-loss. Neuro Oncol 24:741–754.

Chaieb L, Krakau S, Reber TP, Fell J (2022) Modulation of Mind Wandering Using Monaural Beat Stimulation in Subjects With High Trait-Level Mind Wandering. Front Psychol 13:815442.

Chuquisana O, Strippel C, Tröscher AM, Baumgartner T, Rácz A, Keller CW, Elger CE, Melzer N, Kovac S, Wiendl H, Bauer J, Lünemann JD (2022) Complement activation contributes to GAD antibody-associated encephalitis. Acta Neuropathol. doi:10.1007/s00401-022-02448-x.

Cucchi D, Baumgartner T, Walter SG, Menon A, Ossendorff R, Surges R, Burger C, Wirtz DC, Friedrich MJ (2022) Epidemiology and specific features of shoulder injuries in patients affected by epileptic seizures. Arch Orthop Trauma Surg. doi:10.1007/s00402-022-04420-6.

Effert J-S, Esser B, Buschermoehle M, Henze J, Warnecke M, Surges R, Houta S (2022) Usability Engineering for Medical Apps using the Example of an App for Epilepsy Self-Management with a Neurosensing System. In: Human Interaction and Emerging Technologies (IHIET 2022): Artificial Intelligence and Future Applications. AHFE International.

Fell J (2022) What is mind blanking: A conceptual clarification. Eur J Neurosci. doi:10.1111/ejn.15782.

Gentiletti D, Curtis M de, Gnatkovsky V, Suffczynski P (2022) Focal seizures are organized by feedback between neural activity and ion concentration changes. Elife 11.

Gerster M, Waterstraat G, Litvak V, Lehnertz K, Schnitzler A, Florin E, Curio G, Nikulin V (2022) Separating Neural Oscillations from Aperiodic 1/f Activity: Challenges and Recommendations. Neuroinformatics. doi:10.1007/s12021-022-09581-8.

Gozzelino L et al. (2022) Defective lipid signalling caused by mutations in PIK3C2B underlies focal epilepsy. Brain 145:2313–2331.

Grote A, Heiland DH, Taube J, Helmstaedter C, Ravi VM, Will P, Hattingen E, Schüre JR, Witt JA, Reimers A, Elger C, Schramm J, Becker AJ, Delev D (2022) 'Hippocampal innate inflammatory gliosis only' in pharmacoresistant temporal lobe epilepsy. Brain. doi:10.1093/brain/awac293.

Hansen N, Widman G, Önder D, Schwing K, Leelaarporn P, Prusseit I, Wrede R von, Surges R, Becker AJ, Witt J-A, Elger CE, Helmstaedter C (2022) Increased T- and B-cells associated with the phenotype of autoimmune limbic encephalitis with mainly memory dysfunction. J Transl Autoimmun 5:100167.

Harms A, Bauer T, Fischbach L, David B, Ernst L, Witt J-A, Diers K, Baumgartner T, Weber B, Radbruch A, Becker AJ, Helmstaedter C, Reuter M, Elger CE, Surges R, Rüber T (2022) Shape description and volumetry of hippocampus and amygdala in temporal lobe epilepsy - A beneficial combination with a clinical perspective. Epilepsy Behav 128:108560.

Helmstaedter C, Rings T, Buscher L, Janssen B, Alaeddin S, Krause V, Knecht S, Lehnertz K (2022) Stimulation-related modifications of evolving functional brain networks in unresponsive wakefulness. Sci Rep 12:11586.

Henning O, Alfstad KÅ, Johannessen Landmark C, Helmstaedter C, Lossius MI, Holth Skogan A (2022) Use of screening tools to assess comorbidities and adverse events in patients with epilepsy. A European Reference Network for Rare and Complex Epilepsies (EpiCARE) survey. Seizure 101:237–243.

Herreros B, Ruiz de Luna R, La Calle N de, Gayoso D, Martínez P, Olaciregui Dague K, Palacios G (2022) Operation of a triage committee for advanced life support during the COVID-19 pandemic. Philos Ethics Humanit Med 17:5.

Hippen M, Zsurka G, Peeva V, Machts J, Schwiecker K, Debska-Vielhaber G, Wiesner RJ, Vielhaber S, Kunz WS (2022) Novel Pathogenic Sequence Variation m.5789TC Causes NARP Syndrome and Promotes Formation of Deletions of the Mitochondrial Genome. Neurol Genet 8:e660.

Hoppe C, Beeres K, Witt J-A, Sassen R, Helmstaedter C (2022) Clinical adult outcome 11-30 years after pediatric epilepsy surgery: Complications and other surgical adverse events, seizure control, and cure of epilepsy. Epilepsia. doi:10.1111/epi.17477.

Kaaden T et al. (2022) Seizure Semiology in Antibody-Associated Autoimmune Encephalitis. Neurol Neuroimmunol Neuroinflamm 9.

Koko M, Motelow JE, Stanley KE, Bobbili DR, Dhindsa RS, May P (2022) Association of ultra-rare coding variants with genetic generalized epilepsy: A case-control whole exome sequencing study. Epilepsia 63:723–735.

Kutter EF, Boström J, Elger CE, Nieder A, Mormann F (2022) Neuronal codes for arithmetic rule processing in the human brain. Curr Biol. doi:10.1016/j.cub.2022.01.054.

Kyriazi M, Müller P, Pitsch J, van Loo KMJ, Quatraccioni A, Opitz T, Schoch S, Becker AJ, Cases-Cunillera S (2022) Neurochemical profile of BRAFV600E/AktT308D/S473D mouse gangliogliomas reveals impaired GABAergic system inhibition. Dev Neurosci. doi:10.1159/000528587.

Larivière S et al. (2022) Structural network alterations in focal and generalized epilepsy assessed in a worldwide ENIGMA study follow axes of epilepsy risk gene expression. Nat Commun 13:4320.

Lesca G, Baumgartner T, Monin P, Dominicis A de, Kunz WS, Specchio N (2022) Genetic causes of rare and common epilepsies: What should the epileptologist know? European Journal of Medical Genetics 65:104570.

Lichter K, Paul MM, Pauli M, Schoch S, Kollmannsberger P, Stigloher C, Heckmann M, Sirén A-L (2022) Ultrastructural analysis of wild-type and RIM1α knockout active zones in a large cortical synapse. Cell Rep 40:111382.

Lopez SM et al. (2022) Event-based modelling in temporal lobe epilepsy demonstrates progressive atrophy from cross-sectional data. Epilepsia. doi:10.1111/epi.17316.

Luelsberg F, Krakau S, Chaieb L, Witt J-A, Wrede R von, Fell J, Helmstaedter C (2022) Neuropsychological features of mind wandering in left-, right- and extra temporal lobe epilepsy. Seizure 95:50–55.

Matthews EA, Sun W, McMahon SM, Doengi M, Halka L, Anders S, Müller JA, Steinlein P, Vana NS, van Dyk G, Pitsch J, Becker AJ, Pfeifer A, Kavalali ET, Lamprecht A, Henneberger C, Stein V, Schoch S, Dietrich D (2022) Optical analysis of glutamate spread in the neuropil. Cereb Cortex 32:3669–3689.

Mikhailova AG et al. (2022) A mitochondria-specific mutational signature of aging: increased rate of A > G substitutions on the heavy strand. Nucleic Acids Res 50:10264–10277.

Olaciregui-Dague K, Weinhold L, Hoppe C, Schmid M, Surges R (2022) Anti-seizure efficacy and retention rate of carbamazepine is highly variable in randomized controlled trials: a meta-analysis. Epilepsia Open. doi:10.1002/epi4.12644.

Pearl PL, Kunz WS (2022) Lysine Reduction and Cognitive Outcomes in Pyridoxine-Dependent Epilepsy: A New Approach to an Old Disease. Neurology. doi:10.1212/WNL.0000000000201270.

Pohlentz MS, Müller P, Cases-Cunillera S, Opitz T, Surges R, Hamed M, Vatter H, Schoch S, Becker AJ, Pitsch J (2022) Characterisation of NLRP3 pathway-related neuroinflammation in temporal lobe epilepsy. PLoS ONE 17:e0271995.

Pukropski J, Wrede R von, Helmstaedter C, Surges R (2022) Transiente epileptische Amnesie – ein seltenes Phänomen bei Temporallappenepilepsien. Nervenarzt. doi:10.1007/s00115-022-01364-5.

Rácz A, Hummel CA, Becker A, Helmstaedter C, Schuch F, Baumgartner T, Wrede R von, Borger V, Solymosi L, Surges R, Elger CE (2022) Histopathologic Characterization and Neurodegenerative Markers in Patients With Limbic Encephalitis Undergoing Epilepsy Surgery. Front Neurol 13:859868.

Rademacher M, Toledo M, van Paesschen W, Liow KK, Milanov IG, Esch M-L, Wang N, MacPherson M, Byrnes WJ, Minh TDC, Webster E, Werhahn KJ (2022) Efficacy and safety of adjunctive padsevonil in adults with drug-resistant focal epilepsy: Results from two double-blind, randomized, placebo-controlled trials. Epilepsia Open. doi:10.1002/epi4.12656.

Rainey S, Dague KO, Crisp R (2022) Brain-State Transitions, Responsibility, and Personal Identity. Camb Q Healthc Ethics 31:453–463.

Rajbanshi B, Guruacharya A (2022) Panama: An Open-Source Educational App for Ion Channel Biophysics Simulation. Front Neuroinform 16:813940.

Ray A, Bröhl T, Mishra A, Ghosh S, Ghosh D, Kapitaniak T, Dana SK, Hens C (2022) Extreme events in a complex network: Interplay between degree distribution and repulsive interaction. Chaos 32:121103.

Reimers A, Helmstaedter C, Elger CE, Pitsch J, Hamed M, Becker AJ, Witt J-A (2022) Neuropathological insights into unexpected cognitive decline in epilepsy. Ann Neurol. doi:10.1002/ana.26557.

Rings T, Bröhl T, Lehnertz K (2022) Network structure from a characterization of interactions in complex systems. Sci Rep 12:11742.

Schach S, Rings T, Bregulla M, Witt J-A, Bröhl T, Surges R, Wrede R von, Lehnertz K, Helmstaedter C (2022) Electrodermal Activity Biofeedback Alters Evolving Functional Brain Networks in People With Epilepsy, but in a Non-specific Manner. Front Neurosci 16:828283.

Schlömer S et al. (2022) Mid-term treatment-related cognitive sequelae in glioma patients. J Neurooncol 159:65–79.

Schwarz N et al. (2022) Spectrum of Phenotypic, Genetic, and Functional Characteristics in Patients With Epilepsy With KCNC2 Pathogenic Variants. Neurology 98:e2046-e2059.

Silvennoinen K et al. (2022) SCN1A overexpression, associated with a genomic region marked by a risk variant for a common epilepsy, raises seizure susceptibility. Acta Neuropathol. doi:10.1007/s00401-022-02429-0.

Strippel C et al. (2022) A genome-wide association study in autoimmune neurological syndromes with anti-GAD65 autoantibodies. Brain. doi:10.1093/brain/awac119.

Surges R (2022) Autonome Störungen bei epileptischen Anfällen und Epilepsie. In: Das autonome Nervensystem (Weis J, ed), pp 248–269. 70565 Stuttgart: W. Kohlhammer Verlag.

Taube J, Witt J-A, Baumgartner T, Helmstaedter C (2022) All's well that ends well? Long-term course of a patient with anti-amphiphysin associated limbic encephalitis. Epilepsy Behav Rep 18:100534.

Taube J, Witt J-A, Grote A, Delev D, Enkirch J, Hattingen E, Becker AJ, Elger CE, Helmstaedter C (2022) Preoperative and postoperative memory in epilepsy patients with 'gliosis only' versus hippocampal sclerosis: a matched case-control study. J Neurol Neurosurg Psychiatry. doi:10.1136/jnnp-2022-329224.

Taylor C, Tudur-Smith C, Dixon P, Linehan C, Gunko A, Christensen J, Pearson M, Tomson T, Marson A (2022) Care in Europe after presenting to the emergency department with a seizure; position paper and insights from the European Audit of Seizure Management in Hospitals. Eur J Neurol 29:1873–1884.

Tröscher AR et al. (2022) Temporal lobe epilepsy with GAD antibodies: neurons killed by T cells not by complement membrane attack complex. Brain. doi:10.1093/brain/awac404.

Vychopen M, Hamed M, Bahna M, Racz A, Ilic I, Salemdawod A, Schneider M, Lehmann F, Eichhorn L, Bode C, Jacobs AH, Behning C, Schuss P, Güresir E, Vatter H, Borger V (2022) A Validation Study for SHE Score for Acute Subdural Hematoma in the Elderly. Brain Sci 12.

Witt J-A, Helmstaedter C (2022) Do executive deficits differentiate between autoimmune temporal lobe epilepsy and temporal lobe epilepsies with non-autoimmune etiologies? A critical view on recently published data. Epilepsy Behav:108562.

Witt J-A, Helmstaedter C (2022) The impact of perampanel on cognition: A systematic review of studies employing standardized tests in patients with epilepsy. Seizure 94:107–111.

Witt J-A, Rademacher M, Wrede R von, Surges R, Helmstaedter C (2022) Cognitive reawakening and improved quality of life achieved after discontinuing 16 years of anti-seizure treatment with topiramate. Neurocase:1–5.

Witt J-A, Widman G, Hansen N, Wrede R von, Elger CE, Helmstaedter C (2022) Evaluation of a Rapid Topiramate Titration Scheme for the Early Detection of Cognitive Side Effects. CNS Drugs. doi:10.1007/s40263-022-00969-3.

Wrede R von, Bröhl T, Rings T, Pukropski J, Helmstaedter C, Lehnertz K (2022) Modifications of Functional Human Brain Networks by Transcutaneous Auricular Vagus Nerve Stimulation: Impact of Time of Day. Brain Sci 12.

Wrede R von, Rings T, Bröhl T, Pukropski J, Schach S, Helmstaedter C, Lehnertz K (2022) Transcutaneous Auricular Vagus Nerve Stimulation Differently Modifies Functional Brain Networks of Subjects With Different Epilepsy Types. Front Hum Neurosci 16:867563.

Wrede R von, Schidlowski M, Huppertz H-J, Rüber T, Ivo A, Baumgartner T, Hallmann K, Zsurka G, Helmstaedter C, Surges R, Kunz WS (2022) Large Phenotypic Variation of Individuals from a Family with a Novel ASPM Mutation Associated with Microcephaly, Epilepsy, and Behavioral and Cognitive Deficits. Genes (Basel) 13.

Bis 2021

Bahna M, Heimann M, Bode C, Borger V, Eichhorn L, Güresir E, Hamed M, Herrlinger U, Ko Y-D, Lehmann F, Potthoff A-L, Radbruch A, Schaub C, Surges R, Weller J, Vatter H, Schäfer N, Schneider M, Schuss P (2021) Tumor-associated epilepsy in patients with brain metastases: necrosis-to-tumor ratio forecasts postoperative seizure freedom. Neurosurg Rev. doi:10.1007/s10143-021-01560-y.

Bando Y, Wenzel M, Yuste R (2021) Simultaneous two-photon imaging of action potentials and subthreshold inputs in vivo. Nat Commun 12:7229.

Bausch M, Niediek J, Reber TP, Mackay S, Boström J, Elger CE, Mormann F (2021) Concept neurons in the human medial temporal lobe flexibly represent abstract relations between concepts. Nat Commun 12:6164.

Birtel J, Landenberg C von, Gliem M, Gliem C, Reimann J, Kunz WS, Herrmann P, Betz C, Caswell R, Nesbitt V, Kornblum C, Issa PC (2021) Mitochondrial Retinopathy. Ophthalmol Retina. doi:10.1016/j.oret.2021.02.017.

Borger V, Hamed M, Ilic I, Potthoff A-L, Racz A, Schäfer N, Güresir E, Surges R, Herrlinger U, Vatter H, Schneider M, Schuss P (2021) Seizure outcome in temporal glioblastoma surgery: lobectomy as a supratotal resection regime outclasses conventional gross-total resection. J Neurooncol. doi:10.1007/s11060-021-03705-x.

Borger V, Hamed M, Taube J, Aydin G, Ilic I, Schneider M, Schuss P, Güresir E, Becker A, Helmstaedter C, Elger CE, Vatter H (2021) Resective temporal lobe surgery in refractory temporal lobe epilepsy: prognostic factors of postoperative seizure outcome. J Neurosurg 135:760–769.

Boßelmann CM, Antonio-Arce VS, Schulze-Bonhage A, Fauser S, Zacher P, Mayer T, Aparicio J, Albers K, Cloppenborg T, Kunz W, Surges R, Syrbe S, Weber Y, Wolking S (2021) Genetic testing before epilepsy surgery - An exploratory survey and case collection from German epilepsy centers. Seizure 95:4–10.

Chaieb L, Hoppe C, Fell J (2021) Mind wandering and depression: A status report. Neurosci Biobehav Rev 133:104505.

David B, Eberle J, Delev D, Gaubatz J, Prillwitz CC, Wagner J, Schoene-Bake J-C, Luechters G, Radbruch A, Wabbels B, Schramm J, Weber B, Surges R, Elger CE, Rüber T (2021) Multi-scale image analysis and prediction of visual field defects after selective amygdalohippocampectomy. Sci Rep 11:1444.

David B, Kröll-Seger J, Schuch F, Wagner J, Wellmer J, Woermann F, Oehl B, van Paesschen W, Breyer T, Becker A, Vatter H, Hattingen E, Urbach H, Weber B, Surges R, Elger CE, Huppertz H-J, Rüber T (2021) External validation of automated focal cortical dysplasia detection using morphometric analysis. Epilepsia. doi:10.1111/epi.16853.

Debska-Vielhaber G, Miller I, Peeva V, Zuschratter W, Walczak J, Schreiber S, Petri S, Machts J, Vogt S, Szczepanowska J, Gellerich FN, Hermann A, Vielhaber S, Kunz WS (2021) Impairment of mitochondrial oxidative phosphorylation in skin fibroblasts of SALS and FALS patients is rescued by in vitro treatment with ROS scavengers. Exp Neurol 339:113620.

Dehnen G, Kehl MS, Darcher A, Müller TT, Macke JH, Borger V, Surges R, Mormann F (2021) Duplicate Detection of Spike Events: A Relevant Problem in Human Single-Unit Recordings. Brain Sci 11.

Del Bimbo A, Cucchiara R, Sclaroff S, Farinella GM, Mei T, Bertini M, Escalante HJ, Vezzani R (2021) Pattern Recognition. ICPR International Workshops and Challenges. Virtual Event, January 10–15, 2021, Proceedings, Part I. Cham: Springer International Publishing; Imprint Springer.

Derner M, Chaieb L, Dehnen G, Reber TP, Borger V, Surges R, Staresina BP, Mormann F, Fell J (2021) Auditory Beat Stimulation Modulates Memory-Related Single-Neuron Activity in the Human Medial Temporal Lobe. Brain Sci 11.

Dik A, Widman G, Schulte-Mecklenbeck A, Witt J-A, Pitsch J, Golombeck KS, Wagner J, Gallus M, Strippel C, Hansen N, Mönig C, Räuber S, Wiendl H, Elger CE, Surges R, Meuth SG, Helmstaedter C, Gross CC, Becker AJ, Melzer N (2021) Impact of T cells on neurodegeneration in anti-GAD65 limbic encephalitis. Ann Clin Transl Neurol. doi:10.1002/acn3.51486.

Dohrn MF, Medina J, Olaciregui Dague KR, Hund E (2021) Are we creating a new phenotype? Physiological barriers and ethical considerations in the treatment of hereditary transthyretin-amyloidosis. Neurol Res Pract 3:57.

Fauser S, Elger CE, Woermann F, Bien CG (2021) Rasmussen encephalitis: Predisposing factors and their potential role in unilaterality. Epilepsia. doi:10.1111/epi.17131.

Fischbach L, Bauer T, Rüber T, Grobe-Einsler M, Sitter A, Radbruch A, Kaut O (2021) Treatment of progressive multifocal Leukoencephalopathy associated with idiopathic lymphocytopenia with Nivolumab. J Neurol Sci 427:117503.

Gleichgerrcht E et al. (2021) Artificial intelligence for classification of temporal lobe epilepsy with ROI-level MRI data: A worldwide ENIGMA-Epilepsy study. Neuroimage Clin 31:102765.

Haeger A, Pouzat C, Luecken V, N'Diaye K, Elger C, Kennerknecht I, Axmacher N, Dinkelacker V (2021) Face Processing in Developmental Prosopagnosia: Altered Neural Representations in the Fusiform Face Area. Front Behav Neurosci 15:744466.

Helmstaedter C, Solymosi L, Kurthen M, Momjian S, Schaller K (2021) Dr. Strangelove demystified: Disconnection of hand and language dominance explains alien-hand syndrome after corpus callosotomy. Seizure 86:147–151.

Henze J, Houta S, Surges R, Kreuzer J, Bisgin P (2021) Multimodal Detection of Tonic–Clonic Seizures Based on 3D Acceleration and Heart Rate Data from an In-Ear Sensor. In: Pattern Recognition. ICPR International Workshops and Challenges. Virtual Event, January 10–15, 2021, Proceedings, Part I (Del Bimbo A, Cucchiara R, Sclaroff S, Farinella GM, Mei T, Bertini M, Escalante HJ, Vezzani R, eds), pp 490–502. Cham: Springer International Publishing; Imprint Springer.

Jablonski J, Hoffmann L, Blümcke I, Fejtová A, Uebe S, Ekici AB, Gnatkovsky V, Kobow K (2021) Experimental Epileptogenesis in a Cell Culture Model of Primary Neurons from Rat Brain: A Temporal Multi-Scale Study. Cells 10.

Jahanbekam A, Baumann J, Nass RD, Bauckhage C, Hill H, Elger CE, Surges R (2021) Performance of ECG-based seizure detection algorithms strongly depends on training and test conditions. Epilepsia Open. doi:10.1002/epi4.12520.

Kanner AM, Patten A, Ettinger AB, Helmstaedter C, Meador KJ, Malhotra M (2021) Does a psychiatric history play a role in the development of psychiatric adverse events to perampanel… and to placebo? Epilepsy Behav 125:108380.

Kurth JG, Rings T, Lehnertz K (2021) Testing Jump-Diffusion in Epileptic Brain Dynamics: Impact of Daily Rhythms. Entropy (Basel) 23.

Langenbruch L, Strippel C, Görlich D, Elger CE, Möddel G, Meuth SG, Kellinghaus C, Wiendl H, Kovac S (2021) Occurrence of status epilepticus in persons with epilepsy is determined by sex, epilepsy classification, and etiology: a single center cohort study. J Neurol. doi:10.1007/s00415-021-10600-y.

Lehnen NC, Haase R, Faber J, Rüber T, Vatter H, Radbruch A, Schmeel FC (2021) Detection of Degenerative Changes on MR Images of the Lumbar Spine with a Convolutional Neural Network: A Feasibility Study. Diagnostics (Basel) 11.

Leszczynski M, Chaieb L, Staudigl T, Enkirch SJ, Fell J, Schroeder CE (2021) Neural activity in the human anterior thalamus during natural vision. Sci Rep 11:17480.

Lévesque M, Biagini G, Curtis M de, Gnatkovsky V, Pitsch J, Wang S, Avoli M (2021) The pilocarpine model of mesial temporal lobe epilepsy: Over one decade later, with more rodent species and new investigative approaches. Neurosci Biobehav Rev 130:274–291.

Makridis KL, Prager C, Tietze A, Atalay DA, Triller S, Elger CE, Thomale U-W, Kaindl AM (2021) Case Report: Hemispherotomy in the First Days of Life to Treat Drug-Resistant Lesional Epilepsy. Front Neurol 12:818972.

Makridis KL, Triller S, Atalay DA, Prager C, Elger CE, Kaindl AM (2021) Case Report: Behavioral Disorder Following Hemispherotomy: A Valproate Effect? Front Neurol 12:764376.

Moreno-Milan B, Breitbart B, Herreros B, Olaciregui Dague K, Coca Pereira MC (2021) Psychological well-being of palliative care professionals: Who cares? Palliat Support Care 19:257–261.

Mues S, Surges R (2021) Forschung und Entwicklung telemedizinischer Anwendungen und mobiler Gesundheitstechnologien bei Epilepsie. Z. Epileptol. 34:253–256.

Mues S, Surges R (2021) Telemedizin und mobile Gesundheitstechnologien. Z. Epileptol. 34:251–252.

Nass RD, Akgün K, Olaciregui Dague K, Elger CE, Reichmann H, Ziemssen T, Surges R (2021) CSF and Serum Biomarkers of Cerebral Damage in Autoimmune Epilepsy. Front Neurol 12:647428.

Nass RD, Taube J, Bauer T, Rüber T, Surges R, Helmstaedter C (2021) Permanent loss of independence in adult FIRES (Febrile Infection-Related Epilepsy Syndrome) survivors: an underestimated and unsolved challenge. Eur J Neurol. doi:10.1111/ene.14958.

Neuhaus E, Hattingen E, Breuer S, Steidl E, Polomac N, Rosenow F, Rüber T, Herrmann E, Ecker C, Kushan L, Lin A, Vajdi A, Bearden CE, Jurcoane A (2021) Heterotopia in Individuals with 22q11.2 Deletion Syndrome. AJNR Am J Neuroradiol 42:2070–2076.

Neumann K, Schidlowski M, Günther M, Stöcker T, Düzel E (2021) Reliability and Reproducibility of Hadamard Encoded Pseudo-Continuous Arterial Spin Labeling in Healthy Elderly. Front. Neurosci. 15:711898.

Olaciregui Dague K, Pukropski J, Hummel C, Becker A, Surges R, Baumgartner T (2021) Dysphasische Anfälle infolge einer chronischen Leptomeningitis : Eine differenzialdiagnostische Herausforderung. Nervenarzt. doi:10.1007/s00115-021-01190-1.

Pathmanathan J, Kjaer TW, Cole AJ, Delanty N, Surges R, Duun-Henriksen J (2021) Expert Perspective: Who May Benefit Most From the New Ultra Long-Term Subcutaneous EEG Monitoring? Front Neurol 12:817733.

Pensel MC, Basili LM, Jordan A, Surges R (2021) Atrioventricular Conduction in Mesial Temporal Lobe Seizures. Front Neurol 12:661391.

Pitsch J, van Loo KMJ, Gallus M, Dik A, Kamalizade D, Baumgart A-K, Gnatkovsky V, Müller JA, Opitz T, Hicking G, Naik VN, Wachsmuth L, Faber C, Surges R, Kurts C, Schoch S, Melzer N, Becker AJ (2021) CD8+ T-Lymphocyte-Driven Limbic Encephalitis Results in Temporal Lobe Epilepsy. Ann Neurol 89:666–685.

Prillwitz CC, David B, Schlaug G, Deller T, Schramm J, Lindenberg R, Hattingen E, Weber B, Surges R, Elger CE, Rüber T (2021) Functional redundancy of the premotor network in hemispherotomy patients. Ann Clin Transl Neurol. doi:10.1002/acn3.51427.

Rácz A, Becker AJ, Quesada CM, Borger V, Vatter H, Surges R, Elger CE (2021) Post-Surgical Outcome and Its Determining Factors in Patients Operated on With Focal Cortical Dysplasia Type II-A Retrospective Monocenter Study. Front Neurol 12:666056.

Rácz A, Menne K, Borger V, Hampel KG, Vatter H, Helmstaedter C, Elger CE, Surges R (2021) Outcome after resective epilepsy surgery in the elderly. J Neurosurg:1–10.

Reimers A, Hummel CA, Eis-Hübinger AM, Surges R, Niehusmann P, Schoch S, Becker AJ, Pitsch J (2021) Analysis of autoantibody spectrum and human herpesvirus 6 in adult patients with 'early' versus 'late' diagnosis of 'possible limbic encephalitis'. Epilepsy Res 176:106698.

Reiter JT, David B, Enders S, Prillwitz CC, Bauer T, Atalay D, Tietze A, Kaindl AM, Keil V, Radbruch A, Weber B, Becker AJ, Elger CE, Surges R, Rüber T (2021) Infratentorial MRI Findings in Rasmussen Encephalitis Suggest Primary Cerebellar Involvement. Neurol Neuroimmunol Neuroinflamm 8.

Reschke CR, Silva LFA, Vangoor VR, Rosso M, David B, Cavanagh BL, Connolly NMC, Brennan GP, Sanz-Rodriguez A, Mooney C, Batool A, Greene C, Brennan M, Conroy RM, Rüber T, Prehn JHM, Campbell M, Pasterkamp RJ, Henshall DC (2021) Systemic delivery of antagomirs during blood-brain barrier disruption is disease-modifying in experimental epilepsy. Mol Ther 29:2041–2052.

Rick O, Reuß-Borst M, Dauelsberg T, Hass HG, König V, Caspari R, Götz-Keil G, Pfitzner J, Kerschgens C, Fliessbach K, Hoppe C (2021) Einfluss klinischer, sozialmedizinischer und psychologischer Faktoren auf die berufliche Reintegration von Patientinnen mit Brustkrebs 6 Monate nach der Rehabilitation. Rehabilitation (Stuttg). doi:10.1055/a-1288-5824.

Rings T, Wrede R von, Bröhl T, Schach S, Helmstaedter C, Lehnertz K (2021) Impact of Transcutaneous Auricular Vagus Nerve Stimulation on Large-Scale Functional Brain Networks: From Local to Global. Front Physiol 12:700261.

Rodríguez de Los Santos M et al. (2021) A CRISPR-Cas9-engineered mouse model for GPI-anchor deficiency mirrors human phenotypes and exhibits hippocampal synaptic dysfunctions. Proc Natl Acad Sci U S A 118.

Rotko D, Kudin AP, Zsurka G, Kulawiak B, Szewczyk A, Kunz WS (2021) Molecular and Functional Effects of Loss of Cytochrome c Oxidase Subunit 8A. Biochemistry (Mosc) 86:33–43.

Rydin Gorjão L, Witthaut D, Lehnertz K, Lind PG (2021) Arbitrary-Order Finite-Time Corrections for the Kramers-Moyal Operator. Entropy (Basel) 23:517.

Salemdawod A, Wach J, Banat M, Borger V, Hamed M, Haberl H, Sassen R, Radbruch A, Becker AJ, Vatter H, Surges R, Sarikaya-Seiwert S (2021) Predictors of postoperative long-term seizure outcome in pediatric patients with focal cortical dysplasia type II at a German tertiary epilepsy center. Journal of Neurosurgery: Pediatrics:1–9.

Schach S, Surges R, Helmstaedter C (2021) Visual surround suppression in people with epilepsy correlates with attentional-executive functioning, but not with epilepsy or seizure types. Epilepsy Behav 121:108080.

Schidlowski M, Bauer T, David B, Bitzer F, Ostermann L, Racz A, Wrede R von, Radbruch A, Stöcker T, Surges R, Rüber T (2021) Ictal hypoperfusion and iron deposition in symptomatogenic zone of epilepsia partialis continua - A case report. Seizure 89:56–58.

Schoch S, Quatraccioni A, Robens BK, Maresch R, van Loo KMJ, Cases-Cunillera S, Kelly T, Opitz T, Borger V, Dietrich D, Pitsch J, Beck H, Becker AJ (2021) Ste20-like kinase is critical for inhibitory synapse maintenance and its deficiency confers a developmental dendritopathy. J. Neurosci.:JN-RM-0352-21.

Stenton SL et al. (2021) Impaired complex I repair causes recessive Leber's hereditary optic neuropathy. J Clin Invest 131.

Surges R (2021) Autorisierte Übersetzung Zusammenfassung der Praxisleitlinien: Inzidenzraten und Risikofaktoren des plötzlichen unerwarteten Todes bei Epilepsie. Z. Epileptol. 34:202–208.

Surges R (2021) Wearables bei Epilepsien. Klin Neurophysiol 52:29–38.

Surges R, Conrad S, Hamer HM, Schulze-Bonhage A, Staack AM, Steinhoff BJ, Strzelczyk A, Trinka E (2021) SUDEP kompakt – praxisrelevante Erkenntnisse und Empfehlungen zum plötzlichen, unerwarteten Tod bei Epilepsie. Nervenarzt. doi:10.1007/s00115-021-01075-3.

Surges R, Shmuely S, Dietze C, Ryvlin P, Thijs RD (2021) Identifying patients with epilepsy at high risk of cardiac death: signs, risk factors and initial management of high risk of cardiac death. Epileptic Disord. doi:10.1684/epd.2021.1254.

Thijs RD, Ryvlin P, Surges R (2021) Autonomic manifestations of epilepsy: emerging pathways to sudden death? Nat Rev Neurol. doi:10.1038/s41582-021-00574-w.

van Westrhenen A, Shmuely S, Surges R, Diehl B, Friedman D, Leijten FSS, van Smith JH, Benditt DG, van Gert Dijk J, Thijs RD (2021) Timing of syncope in ictal asystole as a guide when considering pacemaker implantation. J Cardiovasc Electrophysiol jce.15239. doi:10.1111/jce.15239.

Willems LM, Baier H, Bien CG, Bösebeck F, Dümpelmann M, Hamer HM, Kellinghaus C, Knake S, Schreiber M, Staack AM, Surges R, Tergau F, Podewils F von, Weber Y, Wehner T, Winter Y, Philipp Zöllner J, Strzelczyk A, Rosenow F (2021) Satisfaction with and reliability of in-hospital video-EEG monitoring systems in epilepsy diagnosis - A German multicenter experience. Clin Neurophysiol. doi:10.1016/j.clinph.2021.04.020.

Witt J-A, Helmstaedter C (2021) Neuropsychological Evaluations in Limbic Encephalitis. Brain Sci 11.

Witt J-A, Meschede C, Helmstaedter C (2021) Hazardous employment of invalid measures for cognitive outcome assessment: You only see what your test can show you. Epilepsy Behav 117:107865.

Wolking S, Campbell C, Stapleton C, McCormack M, Delanty N, Depondt C, Johnson MR, Koeleman BPC, Krause R, Kunz WS, Marson AG, Sander JW, Sills GJ, Striano P, Zara F, Sisodiya SM, Cavalleri GL, Lerche H (2021) Role of Common Genetic Variants for Drug-Resistance to Specific Anti-Seizure Medications. Front Pharmacol 12:688386.

Wolking S et al. (2021) Assessing the role of rare genetic variants in drug-resistant, non-lesional focal epilepsy. Ann Clin Transl Neurol 8:1376–1387.

Wrede R von, Helmstaedter C, Surges R (2021) Cannabidiol in the Treatment of Epilepsy. Clin Drug Investig. doi:10.1007/s40261-021-01003-y.

Wrede R von, Jeub M, Ariöz I, Elger CE, Voss H von, Klein H-G, Becker AJ, Schoch S, Surges R, Kunz WS (2021) Novel KCNH1 Mutations Associated with Epilepsy: Broadening the Phenotypic Spectrum of KCNH1-Associated Diseases. Genes (Basel) 12.

Wrede R von, Meschede C, Brand F, Helmstaedter C (2021) Levetiracetam, perampanel, and the issue of aggression: A self-report study. Epilepsy Behav 117:107806.

Wrede R von, Pukropski J, Moskau-Hartmann S, Surges R, Baumgartner T (2021) COVID-19 vaccination in patients with epilepsy: First experiences in a German tertiary epilepsy center. Epilepsy Behav 122:108160.

Wrede R von, Rings T, Schach S, Helmstaedter C, Lehnertz K (2021) Transcutaneous auricular vagus nerve stimulation induces stabilizing modifications in large-scale functional brain networks: towards understanding the effects of taVNS in subjects with epilepsy. Sci Rep 11:7906.

Wrede R von, Surges R (2021) Patient-zu-Arzt-Anwendungen in der ambulanten Epilepsieversorgung. Z. Epileptol. 34:306–310.

Wrede R von, Surges R (2021) Transcutaneous vagus nerve stimulation in the treatment of drug-resistant epilepsy. Auton Neurosci 235:102840.

Zimmer TS et al. (2021) Seizure-mediated iron accumulation and dysregulated iron metabolism after status epilepticus and in temporal lobe epilepsy. Acta Neuropathol. doi:10.1007/s00401-021-02348-6.

Bauer T, David B, Ernst L, Becker AJ, Witt J-A, Helmstaedter C, Wagner J, Weber B, Elger CE, Surges R, Rüber T (2020) Structural network topology in limbic encephalitis is associated with amygdala enlargement, memory performance and serostatus. Epilepsia 61:e140-e145.

Bauer T, Ernst L, David B, Becker AJ, Wagner J, Witt J-A, Helmstaedter C, Weber B, Hattingen E, Elger CE, Surges R, Rüber T (2020) Fixel-based analysis links white matter characteristics, serostatus and clinical features in limbic encephalitis. Neuroimage Clin 27:102289.

Baxendale SA, Wilson SJ, Baker GA, Barr W, Helmstaedter C, Hermann BP, Langfitt J, Reuner G, Rzezak P, Samson S, Smith M-L (2020) Ten things every neurologist needs to know about neuropsychological assessments and interventions in people with epilepsy. Eur J Neurol 27:215–220.

Beniczky S, Aurlien H, Franceschetti S, Martins da Silva A, Bisulli F, Bentes C, Canafoglia L, Ferri L, Krýsl D, Peralta AR, Rácz A, Cross JH, Arzimanoglou A (2020) Interrater agreement on classification of photoparoxysmal electroencephalographic response. Epilepsia. doi:10.1111/epi.16655.

Borger V, Schneider M, Taube J, Potthoff A-L, Keil VC, Hamed M, Aydin G, Ilic I, Solymosi L, Elger CE, Güresir E, Fimmers R, Schuss P, Helmstaedter C, Surges R, Vatter H (2020) Resection of piriform cortex predicts seizure freedom in temporal lobe epilepsy. Ann Clin Transl Neurol. doi:10.1002/acn3.51263.

Bröhl T, Lehnertz K (2020) Identifying edges that facilitate the generation of extreme events in networked dynamical systems. Chaos 30:73113.

Bröhl T, Rings T, Lehnertz K (2020) Von Interaktionen zu Interaktionsnetzwerken: Zeitabhängige funktionelle Netzwerke am Beispiel der Epilepsie. Klinische Neurophysiologie 51:132–143.

Cox R, Fell J (2020) Analyzing human sleep EEG: A methodological primer with code implementation. Sleep Med Rev 54:101353.

Cox R, Rüber T, Staresina BP, Fell J (2020) Phase-based coordination of hippocampal and neocortical oscillations during human sleep. Commun Biol 3:176.

Cox R, Rüber T, Staresina BP, Fell J (2020) Sharp Wave-Ripples in Human Amygdala and Their Coordination with Hippocampus during NREM Sleep. Cereb Cortex Commun 1:tgaa051.

Delev D, Daka K, Heynckes S, Gaebelein A, Franco P, Pfeifer D, Prinz M, Schnell O, Urbach H, Mader I, Beck J, Grote A, Becker AJ, Heiland DH (2020) Long-term epilepsy-associated tumors: transcriptional signatures reflect clinical course. Sci Rep 10:96.

Delev D, Taube J, Helmstaedter C, Hakvoort K, Grote A, Clusmann H, Lehe M von (2020) Surgery for temporal lobe epilepsy in the elderly: Improving quality of life despite cognitive impairment. Seizure 79:112–119.

Derner M, Dehnen G, Chaieb L, Reber TP, Borger V, Surges R, Staresina BP, Mormann F, Fell J (2020) Patterns of single-neuron activity during associative recognition memory in the human medial temporal lobe. Neuroimage:117214.

Deuschl C, Rüber T, Ernst L, Fendler WP, Kirchner J, Mönninghoff C, Herrmann K, Quesada CM, Forsting M, Elger CE, Umutlu L (2020) 18F-FDG-PET/MRI in the diagnostic work-up of limbic encephalitis. PLoS ONE 15:e0227906.

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Surges R, Sperling MR, DeGiorgio CM (2019) Editorial: Sudden Unexpected Death in Epilepsy: Bio-markers, Mechanisms, Risk Identification and Prevention. Front Neurol 10:1277.

Torregrosa-Muñumer R, Hangas A, Goffart S, Blei D, Zsurka G, Griffith J, Kunz WS, Pohjoismäki JLO (2019) Replication fork rescue in mammalian mitochondria. Sci Rep 9:8785.

Weibel D, Di Francesco R, Kopf R, Fahrni S, Brunner A, Kronenberg P, Lobmaier JS, Reber TP, Mast FW, Wissmath B (2019) TV vs. YouTube: TV Advertisements Capture More Visual Attention, Create More Positive Emotions and Have a Stronger Impact on Implicit Long-Term Memory. Front Psychol 10:626.

Wilkat T, Rings T, Lehnertz K (2019) No evidence for critical slowing down prior to human epileptic seizures. Chaos 29:91104.

Witt J-A, Coras R, Becker AJ, Elger CE, Blümcke I, Helmstaedter C (2019) When does conscious memory become dependent on the hippocampus? The role of memory load and the differential relevance of left hippocampal integrity for short- and long-term aspects of verbal memory performance. Brain Struct Funct 224:1599–1607.

Witt J-A, Krutenko T, Gädeke M, Surges R, Elger CE, Helmstaedter C (2019) Accuracy of expert predictions of seizure freedom after epilepsy surgery. Seizure 70:59–62.

Wrede R von, Moskau-Hartmann S, Amarell N, Elger CE, Helmstaedter C (2019) Knowledge, expectations and fears of cannabis use of epilepsy patients at a tertiary epilepsy center. Epilepsy Behav 99:106458.

Wrede R von, Moskau-Hartmann S, Rüber T, Helmstaedter C, Surges R (2019) Sustained seizure freedom with transcutaneous vagal nerve stimulation in drug-resistant epilepsy caused by subcortical band heterotopias. Seizure 70:25–26.

Abou-Khalil B, Auce P, Avbersek A, ILAE Consortium on Complex Epilepsies (2018) Genome-wide mega-analysis identifies 16 loci and highlights diverse biological mechanisms in the common epilepsies. Nat Commun 9:5269.

Baud MO et al. (2018) European trends in epilepsy surgery. Neurology 91:e96-e106.

Burton A (2018) The enthusiasm of Christian Elger. Lancet Neurol 17:209.

Delev D, Quesada CM, Grote A, Boström JP, Elger CE, Vatter H, Surges R (2018) A multimodal concept for invasive diagnostics and surgery based on neuronavigated voxel-based morphometric MRI postprocessing data in previously nonlesional epilepsy. J Neurosurg 128:1178–1186.

Elger CE (2018) Der Anfall. http://plus.faz.net/natur-und-wissenschaft/2018-01-10/dbc9e146fe28ba17a26f077ed27c371f/?GEPC=s9. Accessed Apr 24, 2019.

Elger CE (2018) Epilepsy: a special disease. Curr Opin Neurol 31:149–150.

Elger CE, Hoppe C (2018) Diagnostic challenges in epilepsy. Seizure under-reporting and seizure detection. Lancet Neurol 17:279–288.

Gruber MJ, Hsieh L-T, Staresina BP, Elger CE, Fell J, Axmacher N, Ranganath C (2018) Theta Phase Synchronization between the Human Hippocampus and Prefrontal Cortex Increases during Encoding of Unexpected Information: A Case Study. J Cogn Neurosci 30:1646–1656.

Hansen N, Chaieb L, Derner M, Hampel KG, Elger CE, Surges R, Staresina B, Axmacher N, Fell J (2018) Memory encoding-related anterior hippocampal potentials are modulated by deep brain stimulation of the entorhinal area. Hippocampus 28:12–17.

Hansen N, Ernst L, Rüber T, Widman G, Becker AJ, Elger CE, Helmstaedter C (2018) Pre- and long-term postoperative courses of hippocampus-associated memory impairment in epilepsy patients with antibody-associated limbic encephalitis and selective amygdalohippocampectomy. E&B 79:93–99.

Hansen N, Widman G, Stuff S, Becker AJ, Witt J-A, Ahmadzadehfar H, Helmstaedter C, Elger CE (2018) Cancer frequency detected by positron emission tomography-computed tomography in limbic encephalitis. Epilepsy Behav 89:105–111.

Helmstaedter C, Elger CE, Vogt VL (2018) Cognitive outcomes more than 5 years after temporal lobe epilepsy surgery: Remarkable functional recovery when seizures are controlled. Seizure 62:116–123.

Helmstaedter C, Beghi E, Elger CE, Kälviäinen R, Malmgren K, May TW, Perucca E, Trinka E, Witt J-A (2018) No Evidence of a Causal Role of Antiepileptic Drug Treatment with Regard to the Development of Dementia. J Am Geriatr Soc 66:1850–1852.

Helmstaedter C, Beghi E, Elger CE, Kälviäinen R, Malmgren K, May TW, Perucca E, Trinka E, Witt J-A (2018) No proof of a causal relationship between antiepileptic drug treatment and incidence of dementia. Comment on: Use of antiepileptic drugs and dementia risk-An analysis of Finnish health register and German health insurance data. Epilepsia 59:1303–1306.

Höller Y, Helmstaedter C, Lehnertz K (2018) Quantitative Pharmaco-Electroencephalography in Antiepileptic Drug Research. CNS Drugs 32:839–848.

Krauss G, Biton V, Harvey JH, Elger CE, Trinka E, Soares da Silva P, Gama H, Cheng H, Grinnell T, Blum D (2018) Influence of titration schedule and maintenance dose on the tolerability of adjunctive eslicarbazepine acetate: An integrated analysis of three randomized placebo-controlled trials. An integrated analysis of three randomized placebo-controlled trials. Epilepsy Res 139:1–8.

Kuhlmann L, Lehnertz K, Richardson MP, Schelter B, Zaveri HP (2018) Seizure prediction - ready for a new era. Nat Rev Neurol 14:618–630.

Kutter EF, Bostroem J, Elger CE, Mormann F, Nieder A (2018) Single Neurons in the Human Brain Encode Numbers. Neuron 100:753-761.e4.

Lamberink HJ, Boshuisen K, Otte WM, Geleijns K, Braun KPJ (2018) Individualized prediction of seizure relapse and outcomes following antiepileptic drug withdrawal after pediatric epilepsy surgery. Epilepsia 59:e28-e33.

Meschede C, Witt J-A, Rademacher M, Wrede RD von, Elger CE, Helmstaedter C (2018) Evaluating the longer-term cognitive effects of adjunctive perampanel compared to lacosamide in a naturalistic outpatient setting. Seizure 58:141–146.

Nass RD, Elger CE, Surges R (2018) Kardiale und zerebrovaskuläre Erkrankungen bei Epilepsie. Z. Epileptol. 31:48–57.

Pitsch J, Kuehn JC, Gnatkovsky V, Müller JA, van Loo KMJ, Curtis M de, Vatter H, Schoch S, Elger CE, Becker AJ (2018) Anti-epileptogenic and Anti-convulsive Effects of Fingolimod in Experimental Temporal Lobe Epilepsy. Mol Neurobiol 12:757.

Prillwitz CC, Rüber T, Reuter M, Montag C, Weber B, Elger CE, Markett S (2018) The salience network and human personality: Integrity of white matter tracts within anterior and posterior salience network relates to the self-directedness character trait. Integrity of white matter tracts within anterior and posterior salience network relates to the self-directedness character trait. Brain Res 1692:66–73.

Rácz A, Müller A-M, Schwerdt J, Becker A, Vatter H, Elger CE (2018) Age at epilepsy onset in patients with focal cortical dysplasias, gangliogliomas and dysembryoplastic neuroepithelial tumours. Seizure:82-89.

Rick O, Reuß-Borst M, Dauelsberg T, Hass HG, König V, Caspari R, Götz-Keil G, Pfitzner J, Kerschgens C, Fliessbach K, Hoppe C (2018) NeuroCog FX study: A multicenter cohort study on cognitive dysfunction in patients with early breast cancer. Psychooncology 27:2016–2022.

Rüber T, David B, Elger CE (2018) MRI in epilepsy: clinical standard and evolution. Curr Opin Neurol 31:223–231.

Rüber T, David B, Lüchters G, Nass RD, Friedman A, Surges R, Stöcker T, Weber B, Deichmann R, Schlaug G, Hattingen E, Elger CE (2018) Evidence for peri-ictal blood-brain barrier dysfunction in patients with epilepsy. Brain 141:2952–2965.

Rydin Gorjão L, Saha A, Ansmann G, Feudel U, Lehnertz K (2018) Complexity and irreducibility of dynamics on networks of networks. Chaos 28:106306.

Schmid E, Thomschewski A, Taylor A, Zimmermann G, Kirschner M, Kobulashvili T, Brigo F, Rados M, Helmstaedter C, Braun K, Trinka E (2018) Diagnostic accuracy of functional magnetic resonance imaging, Wada test, magnetoencephalography, and functional transcranial Doppler sonography for memory and language outcome after epilepsy surgery: A systematic review. Epilepsia 59:2305–2317.

Seyer F, Witt J-A, Taube J, Helmstaedter C (2018) The efficacy of a short-term multidisciplinary epilepsy program. Epilepsy Behav 86:98–101.

Surges R et al. (2018) Aufgaben und Struktur moderner Epilepsiezentren in Deutschland. [Tasks and Structure of Modern Epilepsy Centres in Germany]. Akt Neurol 45:513–533.

Surges R, Wrede R von, Porschen T, Elger CE (2018) Knowledge of sudden unexpected death in epilepsy (SUDEP) among 372 patients attending a German tertiary epilepsy center. E&B 80:360–364.

Trinka E, Ben-Menachem E, Kowacs PA, Elger CE, Keller B, Löffler K, Rocha JF, Soares-da-Silva P (2018) Efficacy and safety of eslicarbazepine acetate versus controlled-release carbamazepine monotherapy in newly diagnosed epilepsy: A phase III double-blind, randomized, parallel-group, multicenter study. A phase III double-blind, randomized, parallel-group, multicenter study. Epilepsia 59:479–491.

Vakharia VN, Duncan JS, Witt J-A, Elger CE, Staba R, Engel J (2018) Getting the best outcomes from epilepsy surgery. Ann Neurol 83:676–690.

Vogt VL, Witt J-A, Delev D, Grote A, Lehe M von, Becker AJ, Schramm J, Elger CE, Helmstaedter C (2018) Cognitive features and surgical outcome of patients with long-term epilepsy-associated tumors (LEATs) within the temporal lobe. Epilepsy Behav 88:25–32.

Vogt VL, Delev D, Grote A, Schramm J, Lehe M von, Elger CE, Witt J-A, Helmstaedter C (2018) Neuropsychological outcome after subtemporal versus transsylvian approach for selective amygdalohippocampectomy in patients with mesial temporal lobe epilepsy: a randomised prospective clinical trial. A randomised prospective clinical trial. J Neurol Neurosurg Psychiatry 89:1057–1063.

Witt J-A, Elger CE, Helmstaedter C (2018) Short-term and longer-term effects of brivaracetam on cognition and behavior in a naturalistic clinical setting-Preliminary data. Seizure 62:49–54.

Bast T, Bauer J, Berkenfeld R, Elger CE, Hamer H, Malter M, Mayer T, Podewils F von, Runge U, Schmidt D, Steinhoff B, Baumgartner C, Oertzen T von, Krämer G, Seeck M, Beyenburg S, Vatter H (2017) Erster epileptischer Anfall und Epilepsien im Erwachsenenalter. [First Epileptic Seizure and Epilepsy in Adulthood]. Akt Neurol 44:603–636.

Becker F, Reid CA, Hallmann K, Tae H-S, Phillips AM, Teodorescu G, Weber YG, Kleefuss-Lie A, Elger CE, Perez-Reyes E, Petrou S, Kunz WS, Lerche H, Maljevic S (2017) Functional variants in HCN4 and CACNA1H may contribute to genetic generalized epilepsy. Epilepsia Open 2:334–342.

Biton V, Rogin JB, Krauss G, Abou-Khalil B, Rocha JF, Moreira J, Gama H, Trinka E, Elger CE, Cheng H, Grinnell T, Blum D (2017) Adjunctive eslicarbazepine acetate: A pooled analysis of three phase III trials. E&B 72:127–134.

Blachut B, Hoppe C, Surges R, Elger CE, Helmstaedter C (2017) Subjective seizure counts by epilepsy clinical drug trial participants are not reliable. E&B 67:122–127.

Blumcke I et al. (2017) Histopathological Findings in Brain Tissue Obtained during Epilepsy Surgery. New England Journal of Medicine 377:1648–1656.

Boström JP, Delev D, Quesada CM, Widman G, Vatter H, Elger CE, Surges R (2017) Stereotaktische Niedrigdosis-Therapie fokaler Epilepsien. Erste Daten einer monozentrischen Machbarkeitsstudie. Z. Epileptol. doi:10.1007/s10309-016-0086-x.

Elger CE (2017) Einflüsse im Gehirn: Wovon hängt ab, wie wir uns entscheiden? In: Was treibt uns an? Motivation und Frustration aus Sicht der Hirnforschung (Gorr C, Bauer MC, eds), pp 23–35. Heidelberg-New York: Springer Science and Business Media; Springer.

Elger CE, Hong SB, Brandt C, Mancione L, Han J, Strohmaier C (2017) BGG492 as an adjunctive treatment in patients with partial-onset seizures: A 12-week, randomized, double-blind, placebo-controlled, phase II dose-titration study with an open-label extension. Epilepsia 58:1217–1226.

Elger CE, Johnston SA, Hoppe C (2017) Diagnosing and treating depression in epilepsy. Seizure 44:184–193.

Elger CE, Koepp M, Trinka E, Villanueva V, Chaves J, Ben-Menachen E, Kowacs PA, Gil-Nagel A, Moreira J, Gama H, Rocha J-F, Soares-da-Silva P (2017) Pooled efficacy and safety of eslicarbazepine acetate as add-on treatment in patients with focal-onset seizures: Data from four double-blind placebo-controlled pivotal phase III clinical studies. CNS Neurosci Ther 23:961–972.

Enkavi AZ, Weber B, Zweyer I, Wagner J, Elger CE, Weber EU, Johnson EJ (2017) Evidence for hippocampal dependence of value-based decisions. Sci Rep 7:17738.

Fisher RS, Acevedo C, Arzimanoglou A, Bogacz A, Cross JH, Elger CE, Engel J, Forsgren L, French JA, Hesdorffer DC, Lee B-I, Mathern GW, Moshe SL, Perucca E, Scheffer IE, Tomson T, Watanabe M, Wiebe S (2017) How long for epilepsy remission in the ILAE definition? Epilepsia 58:1486–1487.

Gorr C, Bauer MC (2017) Was treibt uns an? Motivation und Frustration aus Sicht der Hirnforschung. Heidelberg-New York: Springer Science and Business Media; Springer.

Hampel KG, Elger CE, Surges R (2017) Impaired Baroreflex Sensitivity after Bilateral Convulsive Seizures in Patients with Focal Epilepsy. Front Neurol 8:210.

Hampel KG, Rémi J, Elger CE, Surges R (2017) Diagnostische Fallstricke in der Epileptologie vermeiden. DNP - Der Neurologe & Psychiater 18:44–52.

Hampel KG, Thijs RD, Elger CE, Surges R (2017) Recurrence risk of ictal asystole in epilepsy. Neurology 89:785–791.

Hansen N, Widman G, Hattingen E, Elger CE, Kunz WS (2017) Mesial temporal lobe epilepsy associated with KCNT1 mutation. Seizure 45:181–183.

Hoppe C, Witt J-A, Helmstaedter C, Gasser T, Vatter H, Elger CE (2017) Stereotaktische Laserthermokoagulation in der Epilepsiechirurgie. [Stereotactic laser thermocoagulation in epilepsy surgery]. Nervenarzt 88:397–407.

Hoppe C, Witt J-A, Helmstaedter C, Gasser T, Vatter H, Elger CE (2017) Laser interstitial thermotherapy (LiTT) in epilepsy surgery. Seizure 48:45–52.

Hulbert J, Elger CE, Meyer R, Surges R (2017) Antiepileptic Drugs Impair Shortening of Isolated Cardiomyocytes. Front Neurol 8:133.

Kipervasser S, Elger CE, Korczyn AD, Nass RD, Quesada CM, Neufeld MY (2017) Gait instability in valproate-treated patients: Call to measure ammonia levels. Acta Neurol Scand 136:401–406.

Knieling S, Niediek J, Kutter E, Bostroem J, Elger CE, Mormann F (2017) An online adaptive screening procedure for selective neuronal responses. J Neurosci Methods 291:36–42.

Kudin AP, Baron G, Zsurka G, Hampel KG, Elger CE, Grote A, Weber Y, Lerche H, Thiele H, Nürnberg P, Schulz H, Ruppert A-K, Sander T, Cheng Q, Arnér ES, Schomburg L, Seeher S, Fradejas-Villar N, Schweizer U, Kunz WS (2017) Homozygous mutation in TXNRD1 is associated with genetic generalized epilepsy. Free Radic Biol Med 106:270–277.

Kudin AP, Mawasi H, Eisenkraft A, Elger CE, Bialer M, Kunz WS (2017) Mitochondrial Liver Toxicity of Valproic Acid and Its Acid Derivatives Is Related to Inhibition of α-Lipoamide Dehydrogenase. Int J Mol Sci 18:pii: E1912.

Malviya M et al. (2017) NMDAR encephalitis: passive transfer from man to mouse by a recombinant antibody. Passive transfer from man to mouse by a recombinant antibody. Ann Clin Transl Neurol 4:768–783.

Nass RD, Meiling S, Andrié RP, Elger CE, Surges R (2017) Laboratory markers of cardiac and metabolic complications after generalized tonic-clonic seizures. BMC Neurol 17:187.

Nass RD, Sassen R, Elger CE, Surges R (2017) The role of postictal laboratory blood analyses in the diagnosis and prognosis of seizures. Seizure 47:51–65.

Pintea B, Hampel K, Boström J, Surges R, Vatter H, Lendvai IS, Kinfe TM (2017) Extended Long-Term Effects of Cervical Vagal Nerve Stimulation on Headache Intensity/Frequency and Affective/Cognitive Headache Perception in Drug Resistant Complex-Partial Seizure Patients. Neuromodulation 20:375–382.

Poulheim F, Esposito L, Elger CE, Eis-Hübinger AM, Becker AJ, Niehusmann P (2017) Large-scale analysis of herpesviridae in epilepsy-patients with signs of autoimmune encephalitis. Seizure 53:100–102.

Rácz A, Paus S, Hattingen E, Elger CE, Surges R (2017) Video-EEG findings in acute bithalamic-midbrain ischemia. J Neurol Sci 380:16–18.

Reber TP, Faber J, Niediek J, Boström J, Elger CE, Mormann F (2017) Single-Neuron Correlates of Conscious Perception in the Human Medial Temporal Lobe. Curr Biol 27:2991-2998.e2.

Reuter M, Montag C, Altmann S, Bendlow F, Elger CE, Kirsch P, Becker A, Schoch-McGovern S, Simon M, Weber B, Felten A (2017) Functional characterization of an oxytocin receptor gene variant (rs2268498) previously associated with social cognition by expression analysis in vitro and in human brain biopsy. Soc Neurosci 12:604–611.

Rhein B von, Wagner J, Widman G, Malter MP, Elger CE, Helmstaedter C (2017) Suspected antibody negative autoimmune limbic encephalitis. Outcome of immunotherapy. Acta Neurol Scand 135:134-141.

Schmeiser B, Wagner K, Schulze-Bonhage A, Elger CE, Steinhoff BJ, Wendling A-S, Mader I, Prinz M, Scheiwe C, Zentner J (2017) Transsylvian Selective Amygdalohippocampectomy for Mesiotemporal Epilepsy: Experience with 162 Procedures. Neurosurgery 80:454–464.

Albach H, Meffert H, Pinkwart A, Reichwald R, Eiff W von (2016) Boundaryless Hospital: Rethink and Redefine Health Care Management. Berlin, Heidelberg: Springer Berlin Heidelberg.

Altenmüller D-M, Schulze-Bonhage A, Elger CE, Surges R (2016) Local brain activity persists during apparently generalized postictal EEG suppression. E&B 62:218–224.

Boström JP, Delev D, Quesada C, Widman G, Vatter H, Elger CE, Surges R (2016) Low-dose radiosurgery or hypofractionated stereotactic radiotherapy as treatment option in refractory epilepsy due to epileptogenic lesions in eloquent areas – Preliminary report of feasibility and safety. Seizure 36:57–62.

Bungenberg J, Surano N, Grote A, Surges R, Pernhorst K, Hofmann A, Schoch S, Helmstaedter C, Becker AJ (2016) Gene expression variance in hippocampal tissue of temporal lobe epilepsy patients corresponds to differential memory performance. Neurobiol Dis 86:121–130.

Delev D, Wabbels B, Schramm J, Nelles M, Elger CE, Lehe M von, Clusmann H, Grote A (2016) Vision after trans-sylvian or temporobasal selective amygdalohippocampectomy: a prospective randomised trial. Acta Neurochir (Wien) 158:1757–1765.

Dickten H, Porz S, Elger CE, Lehnertz K (2016) Erratum: Weighted and directed interactions in evolving large-scale epileptic brain networks. Sci Rep 6:38272.

Dickten H, Porz S, Elger CE, Lehnertz K (2016) Weighted and directed interactions in evolving large-scale epileptic brain networks. Sci Rep 6:34824.

Elger CE (2016) Epilepsy in 2015: Classic antiepileptic drugs under fire, and new options emerge. Nat Rev Neurol 12:72–74.

Elger CE (2016) Mit Neuroökonomie aus der Finanzkrise? In: Hirnforschung - was kann sie wirklich? Erfolge, Möglichkeiten und Grenzen (Madeja M, Müller-Jung J, eds), pp 189–198. München: Beck, C H.

Elger CE (2016) The Hospital Situation for Diseases Requiring Sophisticated Examinations Using Epilepsy as an Example. In: Boundaryless Hospital: Rethink and Redefine Health Care Management (Albach H, Meffert H, Pinkwart A, Reichwald R, Eiff W von, eds), pp 249–255. Berlin, Heidelberg: Springer Berlin Heidelberg.

Elger CE (2016) Wider die Vernunft – warum Wirtschaft die Neurowissenschaften braucht. Wirtschaftspsychologie aktuell:21–24.

Elger CE, Rademacher M, Brandt C, Elmoufti S, Dedeken P, Eckhardt K, Tennigkeit F, Backer M de (2016) Changes in hormone and lipid levels in male patients with focal seizures when switched from carbamazepine to lacosamide as adjunctive treatment to levetiracetam: A small phase IIIb, prospective, multicenter, open-label trial. E&B 62:1–5.

Elger CE, Weber B (2016) MRI in presurgical evaluation. In: The treatment of epilepsy (Shorvon SD, Perucca E, Engel J, eds), pp 764–774. Chichester, West Sussex, UK, Hoboken, NJ: John Wiley & Sons Inc.

Elkommos S, Weber B, Niehusmann P, Volmering E, Richardson MP, Goh YY, Marson AG, Elger CE, Keller SS (2016) Hippocampal internal architecture and postoperative seizure outcome in temporal lobe epilepsy due to hippocampal sclerosis. Seizure 35:65–71.

Gast H, Niediek J, Schindler K, Boström J, Coenen VA, Beck H, Elger CE, Mormann F (2016) Burst firing of single neurons in the human medial temporal lobe changes before epileptic seizures. Clin Neurophysiol 127:3329–3334.

Golombeck KS, Bönte K, Mönig C, van Loo KM, Hartwig M, Schwindt W, Widman G, Lindenau M, Becker AJ, Glatzel M, Elger CE, Wiendl H, Meuth SG, Lohmann H, Gross CC, Melzer N (2016) Evidence of a pathogenic role for CD8(+) T cells in anti-GABAB receptor limbic encephalitis. Neurol Neuroimmunol Neuroinflamm 3:e232.

Grote A, Witt J-A, Surges R, Lehe M von, Pieper M, Elger CE, Helmstaedter C, Ormond DR, Schramm J, Delev D (2016) A second chance—reoperation in patients with failed surgery for intractable epilepsy. Long-term outcome, neuropsychology and complications. J Neurol Neurosurg Psychiatry 87:379–385.

Hampel K, Elger CE, Surges R (2016) Epidemiologie, Pathophysiologie und Prävention des SUDEP. [Epidemiology, Pathophysiology and Prevention of SUDEP]. Akt Neurol 43:230–236.

Hampel KG, Jahanbekam A, Elger CE, Surges R (2016) Seizure-related modulation of systemic arterial blood pressure in focal epilepsy. Epilepsia 57:1709–1718.

Hansen N, Widman G, Witt J-A, Wagner J, Becker AJ, Elger CE, Helmstaedter C (2016) Seizure control and cognitive improvement via immunotherapy in late onset epilepsy patients with paraneoplastic versus GAD65 autoantibody-associated limbic encephalitis. E&B 65:18–24.

Helmstaedter C, Elger CE, Witt JA (2016) The effect of quantitative and qualitative antiepileptic drug changes on cognitive recovery after epilepsy surgery. Seizure 36:63–69.

Hoppe C, Elger CE (2016) Epilepsie:Anfallstagebücher im klinischen Alltag und in der Forschung. [Epilepsy: Seizure Diaries in Research and Clinical Practice]. Akt Neurol 43:493-500.

Lehnertz K, Dickten H, Porz S, Helmstaedter C, Elger CE (2016) Predictability of uncontrollable multifocal seizures - towards new treatment options. Sci Rep 6:24584.

Madeja M, Müller-Jung J (2016) Hirnforschung - was kann sie wirklich? Erfolge, Möglichkeiten und Grenzen. München: Beck, C H.

Malter MP, Bahrenberg C, Niehusmann P, Elger CE, Surges R (2016) Features of scalp EEG in unilateral mesial temporal lobe epilepsy due to hippocampal sclerosis: Determining factors and predictive value for epilepsy surgery. Clin Neurophysiol 127:1081–1087.

Malter MP, Widman G, Galldiks N, Stoecker W, Helmstaedter C, Elger CE, Wagner J (2016) Suspected new-onset autoimmune temporal lobe epilepsy with amygdala enlargement. Epilepsia 57:1485–1494.

Möddel G, Esser B, Elger CE (2016) Epilepsien. In: Therapie-Handbuch. Loseblattwerk (2007) mit 30. Aktualisierung 2016. Loseblattwerk inkl. Online-Nutzung. (Sauerbruch T, Diener H-C, Falkai P, eds), 30. Folge P 2. 1-24. München: Elsevier, Urban & Fischer.

Nass RD, Kurth C, Kull A, Graf W, Kasper B, Hamer HM, Strzelczyk A, Elger CE, Steinhoff BJ, Surges R, Rosenow F (2016) Adjunctive retigabine in refractory focal epilepsy: Postmarketing experience at four tertiary epilepsy care centers in Germany. E&B 56:54–58.

Nibber A, Clover L, Pettingill P, Waters P, Elger CE, Bien CG, Vincent A, Lang B (2016) Antibodies to AMPA receptors in Rasmussen's encephalitis. Eur J Paediatr Neurol 20:222–227.

Niediek J, Boström J, Elger CE, Mormann F (2016) Reliable Analysis of Single-Unit Recordings from the Human Brain under Noisy Conditions: Tracking Neurons over Hours. PLoS ONE 11:e0166598.

Reber TP, Do Lam ATA, Axmacher N, Elger CE, Helmstaedter C, Henke K, Fell J (2016) Intracranial EEG correlates of implicit relational inference within the hippocampus. Hippocampus 26:54–66.

Sauerbruch T, Diener H-C, Falkai P (2016) Therapie-Handbuch. Loseblattwerk (2007) mit 30. Aktualisierung 2016. Loseblattwerk inkl. Online-Nutzung. München: Elsevier, Urban & Fischer.

Shmuely S, Surges R, Sander JW, Thijs RD (2016) Prone sleeping and SUDEP risk: The dynamics of body positions in nonfatal convulsive seizures. Epilepsy Behav 62:176–179.

Surges R, Kretschmann A, Abnaof K, van Rikxoort M, Ridder K, Fröhlich H, Danis B, Kaminski RM, Foerch P, Elger CE, Weinsberg F, Pfeifer A (2016) Changes in serum miRNAs following generalized convulsive seizures in human mesial temporal lobe epilepsy. Biochem Biophys Res Commun 481:13–18.

Tomson T, Surges R, Delamont R, Haywood S, Hesdorffer DC (2016) Who to target in sudden unexpected death in epilepsy prevention and how? Risk factors, biomarkers, and intervention study designs. Epilepsia 57 Suppl 1:4–16.

van der Lende M, Surges R, Sander JW, Thijs RD (2016) Cardiac arrhythmias during or after epileptic seizures. J Neurol Neurosurg Psychiatry 87:69–74.

Volmering E, Niehusmann P, Peeva V, Grote A, Zsurka G, Altmüller J, Nürnberg P, Becker AJ, Schoch S, Elger CE, Kunz WS (2016) Neuropathological signs of inflammation correlate with mitochondrial DNA deletions in mesial temporal lobe epilepsy. Acta Neuropathol 132:277–288.

Wagner J, Schoene-Bake J-C, Witt J-A, Helmstaedter C, Malter MP, Stoecker W, Probst C, Weber B, Elger CE (2016) Distinct white matter integrity in glutamic acid decarboxylase and voltage-gated potassium channel-complex antibody-associated limbic encephalitis. Epilepsia 57:475–483.

Baulac M, Boer H de, Elger CE, Glynn M, Kälviäinen R, Little A, Mifsud J, Perucca E, Pitkänen A, Ryvlin P (2015) Epilepsy priorities in Europe: A report of the ILAE-IBE Epilepsy Advocacy Europe Task Force. Epilepsia 56:1687–1695.

Becher A-K, Höhne M, Axmacher N, Chaieb L, Elger CE, Fell J (2015) Intracranial electroencephalography power and phase synchronization changes during monaural and binaural beat stimulation. Eur J Neurosci 41:254–263.

Becker F, Schubert J, Weckhuysen S, Suls A, Grüninger S, Korn-Merker E, Hofmann-Peters A, Sperner J, Cross H, Hallmann K, Elger CE, Kunz WS, Madeleyen R, Lerche H, Weber YG (2015) Do Glut1 (glucose transporter type 1) defects exist in epilepsy patients responding to a ketogenic diet? Epilepsy Res 114:47–51.

Bedarf JR, Marek M, Bien CG, Elger CE, Paus S (2015) Sustained Effect of Botulinum Neurotoxin in Myoclonus Owing to Epilepsia Partialis Continua. Mov Disord Clin Pract 2:402–406.

Blachut B, Hoppe C, Surges R, Stahl J, Elger CE, Helmstaedter C (2015) Counting seizures: The primary outcome measure in epileptology from the patients’ perspective. Seizure 29:97–103.

Boon P et al. (2015) A prospective, multicenter study of cardiac-based seizure detection to activate vagus nerve stimulation. Seizure 32:52–61.

Boshuisen K et al. (2015) Intelligence quotient improves after antiepileptic drug withdrawal following pediatric epilepsy surgery. Ann Neurol 78:104–114.

Chaieb L, Leszczynski M, Axmacher N, Höhne M, Elger CE, Fell J (2015) Theta-gamma phase-phase coupling during working memory maintenance in the human hippocampus. Cogn Neurosci 6:149–157.

Elger CE (2015) Auch langfristig wirksam und sicher. InFo Neurologie 17:22.

Elger CE (2015) Neuropädiatrie: Umfangreiches Nachschlagewerk. Dtsch Arztebl International 112:788-.

Elger CE, Bast T, Schmidt D (2015) Vorsicht bei Valproat für Frauen. Akt Neurol 42:8–10.

Elger CE, Bialer M (2015) Eslicarbazepine Acetate. In: The Treatment of Epilepsy 4 (Shorvon S, Perucca E, Engel J, eds). Oxford, UK: John Wiley & Sons, Ltd.

Esposito L, Drexler JF, Braganza O, Doberentz E, Grote A, Widman G, Drosten C, Eis-Hübinger AM, Schoch S, Elger CE, Becker AJ, Niehusmann P (2015) Large-scale analysis of viral nucleic acid spectrum in temporal lobe epilepsy biopsies. Epilepsia 56:234–243.

Geier C, Bialonski S, Elger CE, Lehnertz K (2015) How important is the seizure onset zone for seizure dynamics? Seizure 25:160–166.

Hampel KG, Vatter H, Elger CE, Surges R (2015) Cardiac-based vagus nerve stimulation reduced seizure duration in a patient with refractory epilepsy. Seizure 26:81–85.

Hoppe C, Feldmann M, Blachut B, Surges R, Elger CE, Helmstaedter C (2015) Novel techniques for automated seizure registration: Patients' wants and needs. E&B 52:1–7.

Hoppe C, Helmstaedter C, Elger CE (2015) Vagus nerve stimulation for epilepsy treatment in children. Epilepsia 56:323–324.

Jehi L, Friedman D, Carlson C, Cascino G, Dewar S, Elger CE, Engel J, Knowlton R, Kuzniecky R, McIntosh A, O'Brien TJ, Spencer D, Sperling MR, Worrell G, Bingaman B, Gonzalez-Martinez J, Doyle W, French J (2015) The evolution of epilepsy surgery between 1991 and 2011 in nine major epilepsy centers across the United States, Germany, and Australia. Epilepsia 56:1526–1533.

Keller SS, Richardson MP, O'Muircheartaigh J, Schoene-Bake J-C, Elger CE, Weber B (2015) Morphometric MRI alterations and postoperative seizure control in refractory temporal lobe epilepsy. Hum Brain Mapp 36:1637–1647.

Keller SS, Richardson MP, Schoene-Bake J-C, O'Muircheartaigh J, Elkommos S, Kreilkamp B, Goh YY, Marson AG, Elger CE, Weber B (2015) Thalamotemporal alteration and postoperative seizures in temporal lobe epilepsy. Ann Neurol 77:760–774.

Lal D et al. (2015) Burden analysis of rare microdeletions suggests a strong impact of neurodevelopmental genes in genetic generalised epilepsies. PLoS Genet. 11:e1005226.

Malter MP, Frisch C, Zeitler H, Surges R, Urbach H, Helmstaedter C, Elger CE, Bien CG (2015) Treatment of immune-mediated temporal lobe epilepsy with GAD antibodies. Seizure 30:57–63.

Mormann F, Niediek J, Tudusciuc O, Quesada CM, Coenen VA, Elger CE, Adolphs R (2015) Neurons in the human amygdala encode face identity, but not gaze direction. Nat Neurosci 18:1568–1570.

Munsell BC, Wee C-Y, Keller SS, Weber B, Elger CE, da Silva LAT, Nesland T, Styner M, Shen D, Bonilha L (2015) Evaluation of machine learning algorithms for treatment outcome prediction in patients with epilepsy based on structural connectome data. Neuroimage 118:219–230.

Nelles M, Urbach H, Sassen R, Schöne-Bake JC, Tschampa H, Träber F, Delev D, Elger CE, Jurcoane A, Hattingen E (2015) Functional hemispherectomy: postoperative motor state and correlation to preoperative DTI. Neuroradiology. Neuroradiology 57:1093–1102.

Noda AH, Reese JP, Berkenfeld R, Dennig D, Endrass G, Kaltofen J, Safavi A, Wiehler S, Carl G, Meier U, Elger CE, Hermsen A, Knake S, Rosenow F, Strzelczyk A (2015) Leitlinienumsetzung und Kosten bei neudiagnostizierter Epilepsie. Z. Epileptol. 28:304–310.

Noda AH, Hermsen A, Berkenfeld R, Dennig D, Endrass G, Kaltofen J, Safavi A, Wiehler S, Carl G, Meier U, Elger CE, Menzler K, Knake S, Rosenow F, Strzelczyk A (2015) Evaluation of costs of epilepsy using an electronic practice management software in Germany. Seizure 26:49–55.

Schmidt D, Surges R, May T, Elger CE (2015) Bestimmung des Nutzens und des Zusatznutzens von Antiepileptika. Eine kritische Übersicht. Akt Neurol 42:323–334.

Staresina BP, Bergmann TO, Bonnefond M, van der Meij R, Jensen O, Deuker L, Elger CE, Axmacher N, Fell J (2015) Hierarchical nesting of slow oscillations, spindles and ripples in the human hippocampus during sleep. Nat Neurosci 18:1679–1686.

Stemmler N, Rohleder K, Malter MP, Widman G, Elger CE, Beck H, Surges R (2015) Serum from a Patient with GAD65 Antibody-Associated Limbic Encephalitis Did Not Alter GABAergic Neurotransmission in Cultured Hippocampal Networks. Front Neurol 6:189.

Surges R, Elger CE (2015) Plötzlicher unerwarteter Tod bei Epilepsie (SUDEP). Arzneimitteltherapie 33:277–287.

Tschampa HJ, Urbach H, Malter M, Surges R, Greschus S, Gieseke J (2015) Magnetic resonance imaging of focal cortical dysplasia: Comparison of 3D and 2D fluid attenuated inversion recovery sequences at 3T. Epilepsy Res 116:8–14.

Tschampa HJ, Urbach H, Träber F, Sprinkart AM, Greschus S, Malter MP, Surges R, Gieseke J, Block W (2015) Proton magnetic resonance spectroscopy in focal cortical dysplasia at 3T. Seizure 32:23–29.

Tsironis T, Hampel K, Elger CE, Surges R (2015) P83. Heart rate is differentially modulated in temporal lobe and psychogenic, non-epileptic seizures. Clin Neurophysiol 126:e143-e144.

Wagner J, Elger CE (2015) Diagnostisches Vorgehen bei Autoimmunenzephalitiden. Z. Epileptol. 28:190–195.

Wagner J, Weber B, Elger CE (2015) Early and chronic gray matter volume changes in limbic encephalitis revealed by voxel-based morphometry. Epilepsia 56:754–761.

Wagner J, Witt J-A, Helmstaedter C, Malter MP, Weber B, Elger CE (2015) Automated volumetry of the mesiotemporal structures in antibody-associated limbic encephalitis. J Neurol Neurosurg Psychiatry 86:735–742.

Widman G, Golombeck K, Hautzel H, Gross CC, Quesada CM, Witt J-A, Rota-Kops E, Ermert J, Greschus S, Surges R, Helmstaedter C, Wiendl H, Melzer N, Elger CE (2015) Treating a GAD65 Antibody-Associated Limbic Encephalitis with Basiliximab: A Case Study. Front Neurol 6:167.

Wiendl H, Elger CE, Förstl H, Hartung H-P, Oertel W, Reichmann H, Schwab S (2015) Gaps between aims and achievements in therapeutic modification of neuronal damage (\"neuroprotection\"). Neurotherapeutics 12:449–454.

Witt J-A, Coras R, Schramm J, Becker AJ, Elger CE, Blümcke I, Helmstaedter C (2015) Relevance of hippocampal integrity for memory outcome after surgical treatment of mesial temporal lobe epilepsy. J Neurol 262:2214–2224.

Witt J-A, Elger CE, Helmstaedter C (2015) Adverse cognitive effects of antiepileptic pharmacotherapy: Each additional drug matters. Eur Neuropsychopharmacol 25:1954–1959.

Witt J-A, Helmstaedter C, Elger CE (2015) Is there evidence of a subordinate role of the hippocampal CA1 field for declarative memory formation? Brain 138:e343.

Witt J-A, Vogt VL, Widman G, Langen K-J, Elger CE, Helmstaedter C (2015) Loss of Autonoetic Awareness of Recent Autobiographical Episodes and Accelerated Long-Term Forgetting in a Patient with Previously Unrecognized Glutamic Acid Decarboxylase Antibody Related Limbic Encephalitis. Front Neurol 6:130.

Wrede R von, Elger CE (2015) Diagnostik und Therapie bei Patienten mit epileptischen Anfällen. Notf.med. up2date 10:173–184.

Zhang H, Fell J, Staresina BP, Weber B, Elger CE, Axmacher N (2015) Gamma power reductions accompany stimulus-specific representations of dynamic events. Curr Biol 25:635–640.

Brelie, Christian von der, Lehe M von, Raabe A, Niehusmann P, Urbach H, Mayer C, Elger CE, Malter MP (2014) Surgical resection can be successful in a large fraction of patients with drug-resistant epilepsy associated with multiple cerebral cavernous malformations. Neurosurgery 74:147-53; discussion 153.

Coenen VA, Elger CE, Schulze-Bonhage A, Urbach H, Reinacher PC, Mädler B (2014) Thalamische Zielgebiete für die tiefe Hirnstimulation bei therapierefraktärer Epilepsie. Z. Epileptol. 27:36–41.

Dejanovic B, Lal D, Catarino CB, Arjune S, Belaidi AA, Trucks H, Vollmar C, Surges R, Kunz WS, Motameny S, Altmüller J, Köhler A, Neubauer BA, Epicure C, Nürnberg P, Noachtar S, Schwarz G, Sander T (2014) Exonic microdeletions of the gephyrin gene impair GABAergic synaptic inhibition in patients with idiopathic generalized epilepsy. Neurobiol Dis 67:88–96.

Duplyakov D, Golovina G, Lyukshina N, Surkova E, Elger CE, Surges R (2014) Syncope, seizure-induced bradycardia and asystole: two cases and review of clinical and pathophysiological features. Seizure 23:506–511.

Elger CE (2014) Epilepsy: lost in translation. Lancet Neurol 13:862–863.

Elger CE (2014) Mit Neuroökonomie aus der Finanzkrise? In: Glanzlichter der Wissenschaft 2014 (Hochschulverband D, ed). Berlin, Boston: De Gruyter.

Fisher RS, Acevedo C, Arzimanoglou A, Bogacz A, Cross JH, Elger CE, Engel,J. ,Jr., Forsgren L, French JA, Glynn M, Hesdorffer DC, Lee BI, Mathern GW, Moshe SL, Perucca E, Scheffer IE, Tomson T, Watanabe M, Wiebe S (2014) ILAE Official Report: A practical clinical definition of epilepsy. Epilepsia 55:475–482.

Hallmann K, Zsurka G, Moskau-Hartmann S, Kirschner J, Korinthenberg R, Ruppert A-K, Ozdemir O, Weber Y, Becker F, Lerche H, Elger CE, Thiele H, Nürnberg P, Sander T, Kunz WS (2014) A homozygous splice-site mutation in CARS2 is associated with progressive myoclonic epilepsy. Neurology 83:2183–2187.

Heers M, Hirschmann J, Jacobs J, Dümpelmann M, Butz M, Lehe M von, Elger CE, Schnitzler A, Wellmer J (2014) Frequency domain beamforming of magnetoencephalographic beta band activity in epilepsy patients with focal cortical dysplasia. Epilepsy Res 108:1195–1203.

Helmstaedter C, May TW, von LM, Pfaefflin M, Ebner A, Pannek HW, Elger CE, Stefan H, Schramm J (2014) Temporal lobe surgery in Germany from 1988 to 2008: diverse trends in etiological subgroups. Eur. J. Neurol. 21:827–834.

Hoppe C, Splittstößer C, Fliessbach K, Trautner P, Elger CE, Weber B (2014) Silent music reading: Auditory imagery and visuotonal modality transfer in singers and non-singers. Brain Cog 91:35–44.

International League Against Epilepsy Consortium on Complex Epilepsies, Richard J L Anney, Andreja Avbersek, David Balding, Larry Baum, (2014) Genetic determinants of common epilepsies: a meta-analysis of genome-wide association studies. Lancet Neurol 13:893–903.

Lamberts RJ, Gaitatzis A, Sander JW, Elger CE, Surges R, Thijs RD (2014) Author response. Neurology 82:1480.

Malmgren K, Rydenhag B, Baxendale S, Thompson PJ, Duncan JS, Shorvon S, Helmstaedter C, Elger CE (2014) Concerns about bilateral radiosurgical treatment of a patient with bilateral temporal lobe epilepsy. Epilepsia 55:623.

Malter MP, Frisch C, Schoene-Bake JC, Helmstaedter C, Wandinger KP, Stoecker W, Urbach H, Surges R, Elger CE, Vincent AV, Bien CG (2014) Outcome of limbic encephalitis with VGKC-complex antibodies: relation to antigenic specificity. J Neurol 261:1695–1705.

Malviya M, Melzer N, Widman G, Elger CE, Wiendl H, Hartung H-P, Goebels N (2014) Autoimmune encephalitis: Single cell PCR analysis of the intrathecal plasma cell repertoire. Journal of Neuroimmunology 275:5.

Markett S, Reuter M, Montag C, Voigt G, Lachmann B, Rudorf S, Elger CE, Weber B (2014) Assessing the function of the fronto-parietal attention network: Insights from resting-state fMRI and the attentional network test. Hum Brain Mapp 35:1700–1709.

Oehrn CR, Hanslmayr S, Fell J, Deuker L, Kremers NA, Do Lam, Anne T, Elger CE, Axmacher N (2014) Neural communication patterns underlying conflict detection, resolution, and adaptation. J. Neurosci. 34:10438–10452.

Schneider C, Helmstaedter C, Luders E, Thompson PM, Toga AW, Elger CE, Weber B (2014) Relation of callosal structure to cognitive abilities in temporal lobe epilepsy. Front Neurol 5:16.

Schoene-Bake J-C, Keller SS, Niehusmann P, Volmering E, Elger CE, Deppe M, Weber B (2014) In vivo mapping of hippocampal subfields in mesial temporal lobe epilepsy: relation to histopathology. Hum Brain Mapp 35:4718–4728.

Surges R (2014) The many facets of cardiac complications in epilepsy. J Neurosci Rural Pract 5:6–7.

Surges R, Elger CE (2014) Mortalität und plötzlicher unerwarteter Tod bei Epilepsie (SUDEP). Fortschr Neurol Psychiatr 82:414.

Vogt VL, Witt J-A, Malter MP, Schoene-Bake J-C, Lehe M von, Elger CE, Helmstaedter C (2014) Neuropsychological outcome after epilepsy surgery in patients with bilateral Ammon's horn sclerosis. J Neurosurg 121:1247–1256.

Witt J-A, Coras R, Schramm J, Becker AJ, Elger CE, Blumcke I, Helmstaedter C (2014) The overall pathological status of the left hippocampus determines preoperative verbal memory performance in left mesial temporal lobe epilepsy. Hippocampus 24:446–454.

Althausen A, Gleissner U, Hoppe C, Sassen R, Buddewig S, Lehe Mv, Schramm J, Elger CE, Helmstaedter C (2013) Long-term outcome of hemispheric surgery at different ages in 61 epilepsy patients. J Neurol Neurosurg Psychiatry 84:529–536.

Ansmann G, Kuhnert MT, Elger CE, Lehnertz K (2013) PRE-SEIZURE STATES IN EPILEPTIC BRAIN NETWORKS: A SURROGATE-ASSISTED, WEIGHTED NETWORK ANALYSIS. In: Recent advance in predicting and preventing epileptic seizures (Elger CE, Lehnertz K, Tetzlaff R, eds), pp 186–196. Singapore, Hackensack, N.J: World Scientific Pub. Co.

Bien CG, Raabe AL, Schramm J, Becker AJ, Urbach H, Elger CE (2013) Trends in presurgical evaluation and surgical treatment of epilepsy at one centre from 1988-2009. J Neurol Neurosurg Psychiatry 84:54–61.

Bien CG, Tiemeier H, Sassen R, Kuczaty S, Urbach H, Lehe Mv, Becker AJ, Bast T, Herkenrath P, Karenfort M, Kruse B, Kurlemann G, Rona S, Schubert-Bast S, Vieker S, Vlaho S, Wilken B, Elger CE (2013) Rasmussen encephalitis: Incidence and course under randomized therapy with tacrolimus or intravenous immunoglobulins. Epilepsia 54:543–550.

Brelie Cvd, Malter MP, Niehusmann P, Elger CE, Lehe Mv, Schramm J (2013) Surgical management and long-term seizure outcome after epilepsy surgery for different types of epilepsy associated with cerebral cavernous malformations. Epilepsia 54:1699–1706.

Cramer J, Elger CE, Halasz P, Hodoba D, Czlonkowska A, Maia J, Almeida L, Soares-da-Silva P (2013) Improvement In Quality-Of-Life And Depressive Symptoms During Long-Term Treatment With Eslicarbazepine Acetate: Bia-2093-301 Study. J Neurol Neurosurg Psychiatry 84:e2.

Deuker L, Olligs J, Fell J, Kranz TA, Mormann F, Montag C, Reuter M, Elger CE, Axmacher N (2013) Memory consolidation by replay of stimulus-specific neural activity. J. Neurosci. 33:19373–19383.

Dickten H, Elger CE, Lehnertz K (2013) MEASURING DIRECTED INTERACTIONS USING CELLULAR NEURAL NETWORKS WITH COMPLEX CONNECTION TOPOLOGIES. In: Recent advance in predicting and preventing epileptic seizures (Elger CE, Lehnertz K, Tetzlaff R, eds), pp 242–252. Singapore, Hackensack, N.J: World Scientific Pub. Co.

Diener H, Weimar C, Berlit P, Deuschl G, Elger CE, Gerloff C, Gold R, Hacke W, Hufschmidt A, Mattle H, Meier U, Oertel W, Reichmann H, Schmutzhard E, Wallesch C-W, Weller M, Kopp I, Olma M, Heuschmann P (2013) Wie entstehen die Leitlinien der Deutschen Gesellschaft für Neurologie? Akt Neurol 39:525–529.

Elger CE (2013) Is valproate contraindicated in young women with epilepsy? No. Epileptology 1:43–45.

Elger CE (2013) Neuroleadership: Erkenntnisse der Hirnforschung für die Führung von Mitarbeitern. Freiburg im Breisgau: Haufe-Lexware.

Elger CE (2013) Therapiefortschritte bei Epilepsie. Drug Res (Stuttg) 63 Suppl 1:S16.

Elger CE, Bialer M, Falcao A, Vaz-da-Silva M, Nunes T, Almeida L, Soares-da-Silva P (2013) Pharmacokinetics and tolerability of eslicarbazepine acetate and oxcarbazepine at steady state in healthy volunteers. Epilepsia 54:1453–1461.

Elger CE, Lehnertz K, Tetzlaff R (2013) Recent advance in predicting and preventing epileptic seizures. Singapore, Hackensack, N.J: World Scientific Pub. Co.

Elger CE, Mormann F (2013) Seizure prediction and documentation-two important problems. Lancet Neurol 12:531–532.

Elger CE, Weber B (2013) Neurophysiologische Werbewahrnehmungs- und Werbewirkungsforschung. In: Dialogmarketing im Dialog (Gerdes J, Hesse J, Vögele S, eds), pp 239–248.

Ermolyuk YS, Alder FG, Surges R, Pavlov IY, Timofeeva Y, Kullmann DM, Volynski KE (2013) Differential triggering of spontaneous glutamate release by P/Q-, N- and R-type Ca2+ channels. Nat Neurosci 16:1754–1763.

Faber J, Schoene-Bake JC, Trautner P, Lehe Mv, Elger CE, Weber B (2013) Progressive fiber tract affections after temporal lobe surgery. Epilepsia 54:e53-e57.

Feis DL, Schoene-Bake JC, Elger CE, Wagner J, Tittgemeyer M, Weber B (2013) Prediction of post-surgical seizure outcome in left mesial temporal lobe epilepsy. Neuroimage.Clin. 2:903–911.

Fell J, Staresina BP, Do Lam AT, Widman G, Helmstaedter C, Elger CE, Axmacher N (2013) Memory modulation by weak synchronous deep brain stimulation: a pilot study. Brain Stimul. 6:270–273.

Frisch C, Malter MP, Elger CE, Helmstaedter C (2013) Neuropsychological course of voltage-gated potassium channel and glutamic acid decarboxylase antibody related limbic encephalitis. Eur. J. Neurol. 20:1297–1304.

Geier C, Kuhnert MT, Elger CE, Lehnertz K (2013) ON THE CENTRALITY OF THE FOCUS IN HUMAN EPILEPTIC BRAIN NETWORKS. In: Recent advance in predicting and preventing epileptic seizures (Elger CE, Lehnertz K, Tetzlaff R, eds), pp 175–185. Singapore, Hackensack, N.J: World Scientific Pub. Co.

Gil-Nagel A, Elger CE, Ben-Menachem E, Halasz P, Lopes-Lima J, Gabbai AA, Nunes T, Falcao A, Almeida L, da-Silva PS (2013) Efficacy and safety of eslicarbazepine acetate as add-on treatment in patients with focal-onset seizures: Integrated analysis of pooled data from double-blind phase III clinical studies. Epilepsia 54:98–107.

Grimminger T, Pernhorst K, Surges R, Niehusmann P, Priebe L, Lehe M von, Hoffmann P, Cichon S, Schoch S, Becker AJ (2013) Levetiracetam resistance: Synaptic signatures & corresponding promoter SNPs in epileptic hippocampi. Neurobiol Dis 60:115–125.

Hagemann A, May TW, Nieder E, Witte-Bolt K, Pohlmann-Eden B, Elger CE, Tergau F, Schulze-Bonhage A, Straub HB, Arnold S, Brandt C (2013) Quality of life, anxiety and depression in adult patients after add-on of levetiracetam and conversion to levetiracetam monotherapy. Epilepsy Res 104:140–150.

Helmstaedter C, Mihov Y, Toliat MR, Thiele H, Nuernberg P, Schoch S, Surges R, Elger CE, Kunz WS, Hurlemann R (2013) Genetic variation in dopaminergic activity is associated with the risk for psychiatric side effects of levetiracetam. Epilepsia 54:36–44.

Hoppe C, Wagner L, Hoffmann JM, Lehe Mv, Elger CE (2013) Comprehensive long-term outcome of best drug treatment with or without add-on vagus nerve stimulation for epilepsy: A retrospective matched pairs case-control study. Seizure 22:109–115.

Krestel H, Raffel S, Lehe Mv, Jagella C, Moskau-Hartmann S, Becker AJ, Elger CE, Seeburg PH, Nirkko A (2013) Differences between RNA and DNA due to RNA editing in temporal lobe epilepsy. Neurobiol.Dis. 56C:66–73.

Kuss K, Falk A, Trautner P, Elger CE, Weber B, Fliessbach K (2013) A reward prediction error for charitable donations reveals outcome orientation of donators. Soc.Cogn Affect.Neurosci. 8:216–223.

Lal D et al. (2013) Rare exonic deletions of the RBFOX1 gene increase risk of idiopathic generalized epilepsy. Epilepsia 54:265–271.

Lamberts RJ, Gaitatzis A, Sander JW, Elger CE, Surges R, Thijs RD (2013) Postictal generalized EEG suppression: An inconsistent finding in people with multiple seizures. Neurology 81:1252–1256.

Lamberts RJ, Gaitatzis A, Sander JW, Elger CE, Surges R, Thijs RD (2013) Postictal generalized EEG suppression: an inconsistent finding in people with multiple seizures. Neurology 81:1252–1256.

Malter MP, Elger CE, Surges R (2013) Diagnostic value of CSF findings in antibody-associated limbic and anti-NMDAR-encephalitis. Seizure 22:136–140.

Malter MP, Tschampa HJ, Helmstaedter C, Urbach H, Lehe Mv, Becker AJ, Clusmann H, Elger CE, Bien CG (2013) Outcome after epilepsy surgery in patients with MRI features of bilateral ammon's horn sclerosis. Epilepsy Res 105:150–157.

Markett S, Weber B, Voigt G, Montag C, Felten A, Elger CE, Reuter M (2013) Intrinsic connectivity networks and personality: The temperament dimension harm avoidance moderates functional connectivity in the resting brain. Neuroscience 240:98–105.

Möddel G, Elger CE (2013) Resektion, Stimulation oder Diät? Nicht-medikamentöse Epilepsietherapie. NeuroTransmitter 5:62–70.

Rocamora R, Andrzejak RG, Jimenez-Conde J, Elger CE (2013) Sleep modulation of epileptic activity in mesial and neocortical temporal lobe epilepsy: A study with depth and subdural electrodes. E&B 28:185–190.

Sammler D, Koelsch S, Ball T, Brandt A, Grigutsch M, Huppertz HJ, Knosche TR, Wellmer J, Widman G, Elger CE, Friederici AD, Schulze-Bonhage A (2013) Co-localizing linguistic and musical syntax with intracranial EEG. Neuroimage 64:134–146.

Semmler A, Moskau-Hartmann S, Stoffel-Wagner B, Elger CE, Linnebank M (2013) Homocysteine plasma levels in patients treated with antiepileptic drugs depend on folate and vitamin B12 serum levels, but not on genetic variants of homocysteine metabolism. Clin.Chem.Lab Med. 51:665–669.

Sheanon E, Pitkänen A (2013) Epilepsy on the horizon: Dublin forum focused on epilepsy care and research in Europe. Epilepsia 54:1713–1714.

Steinhoff BJ, Elger CE, Perucca E (2013) Kürzlich eingeführte Antiepileptika. In: Perspektiven der pharmakologischen Behandlung von Epilepsien (Lerche H, Potschka H, eds), pp 58–67. UNI-MED.

Steinhoff BJ, Elger CE, Perucca E (2013) Recently marketed drugs. In: Therapeutic targets and perspectives in the pharmacological treatment of epilepsy (Lerche H, ed), pp 52–60. Bremen: UNI-MED-Verl.

Surges R, Elger CE (2013) Reoperation after failed resective epilepsy surgery. Seizure 22:493–501.

Surges R, Jordan A, Elger CE (2013) Ictal modulation of cardiac repolarization, but not of heart rate, is lateralized in mesial temporal lobe epilepsy. PLoS ONE 8:e64765.

Surges R, Sander JW, Wojczal J, Halczuk I (2013) Nagly niespodziewany zgon w padaczce : mechanizmy, czestosc wystepowania oraz zapobieganie. Neurologia Praktyczna:25–36.

Wagner J, Schoene-Bake JC, Malter MP, Urbach H, Huppertz HJ, Elger CE, Weber B (2013) Quantitative FLAIR analysis indicates predominant affection of the amygdala in antibody-associated limbic encephalitis. Epilepsia 54:1679–1687.

Wellmer J, Quesada CM, Rothe L, Elger CE, Bien CG, Urbach H (2013) Proposal for a magnetic resonance imaging protocol for the detection of epileptogenic lesions at early outpatient stages. Epilepsia 54:1977–1987.

Witt J-A, Elger CE, Helmstaedter C (2013) Impaired verbal fluency under topiramate - evidence for synergistic negative effects of epilepsy, topiramate, and polytherapy. Eur. J. Neurol. 20:130–137.

Witt J-A, Elger CE, Helmstaedter C (2013) Which drug-induced side effects would be tolerated in the prospect of seizure control? E&B 29:141–143.

Wrede R von, Moskau-Hartmann S, Elger CE (2013) Diagnostik, Prophylaxe und Therapie bei neurochirurgischen Patienten mit epileptischen Anfällen. Neurochir Scan 01:205–223.