Magnetic Resonance Spectroscopy (MRS)

MR spectroscopy addresses the non-invasive detection of small molecules in the organism (e.g. N-acetylaspartate, choline, lactate, phosphocreatine). Analyses of the in-vivo concentrations of such metabolites in body tissue are mainly performed at the 3T-high-field MRI with proton(1H)- and phosphorus(31P)-MRS. MRS is scientifically applied for the following diseases: Neurodegenerative diseases (e.g. neurodegenerative diseases (e.g. amyotrophic lateral sclerosis, including motor neuron diseases, Alzheimer's disease), neuro-inflammatory diseases (e.g. multiple sclerosis, leukodystrophy), schizophrenia and brain tumours. The MRS is also used as in-vivo gold standard in MR-relaxometry as well as for the determination of the proton density fat fraction.